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OpenTrials
Completed

NCT Number: NCT03650374

Effects of Contralateral Strength Training on Postoperative Strength Deficits in the Immobilized Lower Extremity

This is a prospective, randomized controlled trial that will enroll patients undergoing unilateral meniscal root repair or meniscus transplant. The objective of this study is to determine if immediate postoperative strength training of the contralateral (non-surgical) lower extremity reduces postoperative loss of strength in an immobilized lower extremity.

After the completion of surgery, patients will be randomized to either the experimental treatment (Group 1) or control group (Group II)for postoperative rehabilitation.

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Key information

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

New York University School of Medicine

New York, 10016, United States

About this study

Group I will receive knee flexion and extension strength training exercises for the contralateral (non-operative) lower extremity in addition to standard of care postoperative rehabilitation. The experimental strength training will be performed with moderate resistance and will require moderate effort. Exercises will include unilateral leg presses, lunges, step ups, and step downs. These exercises are performed as standard of care but are not typically introduced into the physical therapy regimen until 10-12 weeks postoperatively. In the experimental group, these exercises will be introduced starting with the first postoperative physical therapy session, but only for the contralateral (non-operative) leg.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient is indicated for meniscal root repair
  • Patient is indicated for meniscus transplant
  • Patient is at least 18 years of age
  • Patient is expected to survive at least 1 year beyond surgery
  • Patient has intact lower extremities bilaterally
  • Patient is willing to participate by complying with pre-and post-operative visit requirements
  • Patient is willing and able to review and sign a study informed consent form

Exclusion criteria

  • Lower extremity musculoskeletal defects
  • Systemic neuromuscular disorders
  • Failure to complete pre-operative BIDOEX strength assessment
  • Failure to complete pre-operative self-assessment score intake forms

Treatment and study plan

Standard of Care Rehabilitation

Other

Knee flexion and extension strength training exercises for the contralateral (non-operative) lower extremity in addition to standard of care postoperative rehabilitation.

Experimental Strength Training

Other

Will be performed with moderate resistance and will require moderate effort. Exercises will include unilateral leg presses, lunges, step ups, and step downs. These exercises are performed as standard of care but are not typically introduced into the physical therapy regimen until 10-12 weeks postoperatively. In the experimental group, these exercises will be introduced starting with the first postoperative physical therapy session, but only for the contralateral (non-operative) leg.

Primary outcomes

  1. KOOS

    Time frame: 6 Weeks, 3 Months, 6 Months

    A patient-reported outcome measurement instrument, developed to assess the patient's opinion about their knee and associated problems.

Sponsors and collaborators

Lead sponsor

NYU Langone Health

Other

Registry information

Important dates

Study start
2021
Primary completion
2025
Study completion
2025
First posted
Aug 28, 2018
Registry last updated
Mar 30, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.