Skip to main content
OpenTrials
Completed

NCT Number: NCT05768581

Effects of Concurrent Training on Physical Fitness and Body Composition in Obese Individuals

Ample evidence demonstrates the beneficial role of physical activity combined with a structured dietary plan to counteract obesity. International guidelines as the World Health Organization states that to improve fitness levels at least 150 min a week of physical activity at moderate intensity, combined with resistance training composed of 8-12 repetitions with an intensity of 60-70%1RM for each muscle group, are recommended. In this regard, a minimum dosage of 60-90 min of physical activity composed by aerobic exercises in alternation with resistance training protocols, allow a sequential development of cardiorespiratory fitness and muscular strength parameters avoiding potential interference effects. Interference may occur when strength and endurance stimuli both target opposite peripheral adaptations (e.g., hypertrophy vs. muscle capillarization) and this phenomenon seems to be particularly clear during adolescence. Nevertheless, the incorporation of different training stimuli within the same training session is called Concurrent Training. This training mode, thanks to the activation of two different metabolic pathways (e.g., aerobic and anaerobic), has a variety, beneficial effects in terms of muscle mass and strength development, body composition profile regulation and neuromotor function improvement. Concurrent Training seems to be effective not only in normal-weight subjects, but also in obese individuals, reporting positive adaptations on physical fitness and health status compared with a single-mode (i.e., aerobic or strength training). Therefore, the aim of this study is to detect the effects of a 10-week-Concurrent Training protocol compared with a single training modality on physical fitness, body composition and circadian rhythms in adult outpatients with obesity.

Completed

Looking for future studies?

Notify Me

Key information

Age range

25 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Istituto Auxologico Italiano IRCCS

Milan, 20145, Italy

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Physical activity frequency minor of 2 days/week
  • BMI major of 30 kg/m2
  • informed consent signature

Exclusion criteria

  • age over 65 years
  • knee or hip pain (visual analogue scale score >7 arbitrary units
  • a history of hip, knee or foot replacement or osteoarthrosis
  • cardiac infarction
  • neurological impairments or any other clinical condition that affects the practice of physical activity

Treatment and study plan

Concurrent training

Other

Participants should perform strength training and aerobic exercises

Strength training

Other

Participants should perform strength exercises

Aerobic training

Other

Participants should perform aerobic exercises

Primary outcomes

  1. Change from baseline strength in kilograms at 10 weeks

    Time frame: Up to 10 weeks

    Maximum isometric handgrip strength using a dynamometer

  2. Change from baseline cardiorespiratory fitness in number of steps performed at 10 weeks fitness

    Time frame: Up to 10 weeks

    Maximum aerobic capacity using the two minute step test

  3. Change from baseline postural control in arbitrary units at 10 weeks

    Time frame: Up to 10 weeks

    Balance and postural control using the Balance Error Scoring System

Secondary outcomes

  1. Change from baseline fat mass percentage at 10 weeks

    Time frame: Up to 10 weeks

    Fat mass % using a Tetrapolar Bioelectrical Impedance

  2. Change from baseline weight in kilograms at 10 weeks

    Time frame: Up to 10 weeks

    weight status using weight scale

  3. Change from baseline height in meters at 10 weeks

    Time frame: Up to 10 weeks

    height using a stadiometer

  4. Change from baseline waist circumference in centimeters at 10 weeks

    Time frame: Up to 10 weeks

    waist circumference using a 200 cm tape

  5. Change from baseline circadian rhythm in arbitrary units at 10 weeks

    Time frame: Up to 10 weeks

    Chronotype profile using Morningness-Eveningness Questionnaire

Sponsors and collaborators

Lead sponsor

Istituto Auxologico Italiano

Other

Registry information

Official study title

Effects of a Concurrent Home-based Training on Cardiorespiratory Fitness, Muscular Strength, Balance, Daily-life Activities and Body Composition in Obese Individuals

Acronym: CONCOB

Important dates

Study start
2022
Primary completion
2023
Study completion
2024
First posted
Mar 14, 2023
Registry last updated
Aug 21, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.