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NCT Number: NCT06845436

Effects of Combined High Intensity Interval Training and Resistance Training

Background: Hypertension has long been considered as a major risk factor for cardiovascular disease representing a high public health concern.

Objectives: the purpose of this study is to evaluate the effects of combined HIIT and resistance training on body composition, blood pressure, and cardiorespiratory fitness in obese hypertensive men.

Methods: This study will make use of sixty obese hypertensive men aged 40 to 60 years. All participants meeting the eligibility criteria will be assigned to one of three groups; combined HIIT and resistance group, HIIT only group or control group. Combined exercise group subjects will undergo weekly three sessions of both HIIT and resistance training for sixteen weeks. The HIIT session will involve four four-minute high-intensity intervals with an intensity of at 80-95% of the HRmax interspersed with two-minute active recovery intervals with intensity of 40% to 60% of the HRmax. The resistance training session will be composed of eight exercises perform 3 sets of 8-12 repetitions with an intensity of 80% of the subject's estimated 1-RM. The HIIT only group perform 12 weeks of HIIT only. The control group subjects will be instructed not to change their usual daily physical activities routine and instructed to abstain from practicing any exercise regimens during the 12-week study period. Body composition measures, blood pressure and VO2peak will be assessed at baseline and at the end of the study period.

Results: All the outcome variables will be assessed at baseline and 12 weeks following the treatment period.

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Key information

Age range

40 year–60 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Prince Sattam bin Abdulaziz University

Riyadh, Alkharj, 16278, Saudi Arabia

Location status: Recruiting

Location contact

Ahmed Sayed Ahmed

CONTACT

[email protected]

+966564347031

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • men aged between 40 and 60 years old,
  • have been diagnosed with clinical stage 1 or 2 hypertension,
  • being obese with body mass index more than 30 kg/m2
  • physically inactive

Exclusion criteria

  • musculoskeletal problems that may limit their ability to participate in resistance or HIIT programs
  • diabetes mellitus
  • a history of respiratory or chronic heart disease

Treatment and study plan

Exercise

Behavioral

Combined exercise group subjects will undergo weekly three sessions of both HIIT and resistance training for sixteen weeks. The HIIT session will involve four four-minute high-intensity intervals with an intensity of at 80-95% of the HRmax interspersed with two-minute active recovery intervals with intensity of 40% to 60% of the HRmax.

routine physical activity

Other

The control group subjects will be instructed not to change their usual daily physical activities routine and instructed to abstain from practicing any exercise regimens during the 12-week study period.

Primary outcomes

  1. blood pressure in mmhg

    Time frame: 12 weeks

  2. peak oxygen consumption in ml/kg/min

    Time frame: 12 weeks

  3. body weight in Kg

    Time frame: 12 weeks

  4. body mass index in kg/m2

    Time frame: 12 weeks

Study contacts

Contact information is provided by the study sponsor or research team.

Ahmed S Ahmed, PhD

CONTACT

[email protected]

000966564347031 ext. 00966115886326

Sponsors and collaborators

Lead sponsor

Prince Sattam Bin Abdulaziz University

Other

Registry information

Official study title

Effects of Combined High Intensity Interval Training and Resistance Training on Body Composition, Blood Pressure, and Cardiorespiratory Fitness in Obese Hypertensive Men

Acronym: Hypertension

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Feb 25, 2025
Registry last updated
Jun 4, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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