Rehab lab, Pusan National University Yangsan Hospital
Yangsan, Gyeongsangnam-do, 50612, South Korea
Location status: Recruiting
Recruiting
NCT Number: NCT07324226
Effects of Combined Heat Application and Acupressure to the Carotid Artery Region on Cerebral Blood Flow in Healthy Adults
The aim of this study is to investigate the effects of combined heat application and acupressure to the carotid artery region on cerebral blood flow in healthy adults
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
40 year–65 year
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Adults aged 40 to 65 years.
- Individuals with no history of cerebrovascular, cardiovascular, or neurological diseases.
- Individuals who have signed the informed consent form and voluntarily agreed to participate in the study
Exclusion criteria
- Individuals with a history of cerebrovascular, cardiovascular, or neurological diseases (e.g., stroke, angina, epilepsy).
Individuals currently taking medications that may affect cerebral blood flow (such as antihypertensive agents or antidepressants).
Individuals with skin diseases or lesions that make it difficult to apply heat or acupressure devices to the carotid artery region, and individuals who are pregnant or breastfeeding.
Individuals with a history of seizures.
Individuals who have participated in clinical studies two or more times in the same year, or who have participated in another clinical study within the past 6 months.
Individuals who, in the judgment of the principal investigator or sub-investigator, have clinically significant findings that make them unsuitable for participation in this study.
Treatment and study plan
Combined heat and acupressure
DevicePress the start button to activate the automatic mode. When the start button is pressed, the device operates for approximately 40 minutes.
When the start button is pressed, acupressure massage is performed with a single back-and-forth cycle from acupressure bar No. 1 to No. 18.
The device then performs back-and-forth acupressure massage between acupressure bars No. 18 and No. 13 for the remaining time.
After operating for 40 minutes in automatic mode, the mattress heating unit, the acupressure bar heating unit, and the acupressure bar movement are all turned off.
- Press the shoulder button. The acupressure bar operates in the neck-to-shoulder section (acupressure bars No. 1 to 6), and both the mattress heating unit and the acupressure bar heating unit are activated.
- After operating for 20 minutes in manual mode, the mattress heating unit, the acupressure bar heating unit, and the acupressure bar movement are turned off.
Primary outcomes
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A SPECT CT brain scan
Time frame: In the post-SPECT protocol, the radiopharmaceutical will be administered at 5 minutes (n=3), 10 minutes (n=3), and 20 minutes (n=3) after the start of image acquisition.
Cerebral blood flow change rate analysis: For each participant, the percentage change in cerebral blood flow (CBF) observed on SPECT imaging compared with the baseline time point will be quantitatively analyzed at the following three time points.
Radiopharmaceutical injection reference times: 5 minutes, 10 minutes, and 20 minutes after injection.
Study contacts
Contact information is provided by the study sponsor or research team.
Sponsors and collaborators
Lead sponsor
Pusan National University Yangsan Hospital
Other
Registry information
Official study title
Effects of Combined Heat Application and Acupressure to the Carotid Artery Region on Cerebral Blood Flow in Healthy Adults: An Investigator-Initiated, Single-Group, Single-Center, Prospective Case Study
Important dates
- Study start
- 2026
- Primary completion
- 2026
- Study completion
- 2026
- First posted
- Jan 7, 2026
- Registry last updated
- Jan 7, 2026
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.