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NCT Number: NCT07244146

Effects of CHRIST Among Children With Spastic CP

This Quasi experimental study investigates the effects of CHRIST on In Hand Manipulation and Grip Strength amonfg children with Spastic Cerebral Palsy. The study involves 14 children from 6-12 years of age, and will be given intervention for 10 weeks period.

Key performance outcomes- In Hand Manipulation and Grip Strength will be assessed both before and after the intervention. This study aims to address this gap by evaluating the effects of the CHRIST on IHM and grip strength in children diagnosed with spastic cerebral palsy. The hypothesis is that integrating strength training with high repetition, functionally relevant tasks yields greater and more practical gains than strength training or conventional therapy alone. Data will be analyzed through SPSS version 27.0

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Key information

Age range

6 year–12 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

About this study

This Quasi Experimental study investigates the effects of CHRIST on In Hand Manipulation and Grip Strength in children with Spastic Cerebral Palsy. CHRIST was designed to enhance the motor ability of children. The efficacy of this program will be investigated through a Quasi Experimental study. Data will be collected from special schools and rehabilitation centers having children with spastic cerebral palsy. The intervention CHRIST will be given thrice a week for forty minutes. The study will be completed in 10 weeks after approval of the synopsis. The study will include 14 children, male and female. Inclusion criteria for the study will include patients diagnosed with spastic CP. Data will be collected from children aged 6 to 12 years old. IHM will be measured by Melbourne Assessment 2 scale (MA2). Grip Strength will be measured by dynamometer. IHM & Grip Strength will be assessed both before and after the intervention.This study aims to address this gap by evaluating the effects of CHRIST on IHM and grip strength in children diagnosed with spastic cerebral palsy. The hypothesis is that integrating strength training with high repetition, functionally relevant tasks yields greater and more practical gains than strength training or conventional therapy alone. Data will be analyzed through SPSS version 27.0

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Children Diagnosed with hemiplegic spastic cerebral palsy.
  • Age 6-12 years.
  • Capable of following commands regarding hand use and testing.
  • Capable of communicating needs.
  • Parents or caregivers willing to provide informed consent and participate in the study.
  • No contraindications to moderate physical activity.
  • Able to lift the more affected arm 15 cm above a table surface and grasp light objects

Exclusion criteria

  • Children with musculoskeletal system injuries, including upper limb fractures or contractures, as well as those who had received medications affecting muscle strength or spasticity, were excluded from the study.
  • Orthopedic surgery involving the more affected hand within the past 6 months.
  • Children with Cardiovascular disease.
  • Lack of cooperation with instructions or other behavioral challenges that prevent effective delivery of intensive therapy.
  • Visual impairments that may hinder active participation.
  • Seizure or family history of seizure disorders

Treatment and study plan

CHRIST

Other

CHRIST, is a treadmill-based training with body weight supported by the upper limbs. There will be a session of 40 minutes, which includes 3 sets (10 minutes exercise with 3 minutes rest period per set), three times a week, over a 10 week period. By maintaining the posture of the quadruped, the abdomen and weight of the lower limb will be supported by using a support board under the abdomen. The speed of the treadmill for the upper limbs will be 0.3-1.2 km/h.

Primary outcomes

  1. Jamma Dynamometer

    Time frame: Baseline, 1st week and 10th week

    Grip strength will be measured by Jammar Dynamometer. The hand-held dynamometer are reliable measurement instruments to measure muscle strength of the arm and hand in children with unilateral spastic cerebral palsy, aged 7 12 years

Secondary outcomes

  1. Melbourne assessment 2 (MA2)

    Time frame: Baseline, 1st week and 10th week

    Melbourne Assessment 2 (MA2) will be used to assess in-hand manipulation before and after the intervention (CHRIST) to evaluate the impact. MA2 is a reliable and valid tool for assessment of upper limb in children with CP.

Study contacts

Contact information is provided by the study sponsor or research team.

IMRAN AMJAD, PHD

CONTACT

[email protected]

9233224390125

MUHAMMAD ASIF JAVED, MSPT

CONTACT

[email protected]

923224209422

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Official study title

Effects of Comprehensive Hand Intense Strength Training on In Hand Manipulation and Grip Strength Among Children With Spastic Cerebral Palsy

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Nov 24, 2025
Registry last updated
Nov 24, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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