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NCT Number: NCT07092878

Effects of Chamomile With L-theanine Beverage Among Young Women Experiencing Primary Dysmenorrhea

This study aims to evaluate the effects of a beverage containing chamomile and L-theanine on menstrual symptoms, pain intensity, mood, and sleep quality among young adult females with primary dysmenorrhea.

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Key information

Conditions

Primary Dysmenorrhea

Age range

18 year–30 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

About this study

This study aims to evaluate the effects of a beverage containing chamomile and L-theanine on menstrual symptoms, pain intensity, mood, and sleep quality among young adult females with primary dysmenorrhea.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • A VAS score of ≥4 cm for the past three consecutive menstrual cycles
  • Regular monthly menstruation
  • No history of allergies or psychological/gynecological illnesses
  • Absence of secondary dysmenorrhea
  • No current use of any medications
  • No ongoing non-pharmacological management for dysmenorrhea.

Exclusion criteria

  • Pregnant
  • Breastfeeding

Treatment and study plan

Chamomile (Matricaria recutita)

Dietary Supplement

Participants in the intervention group will consume the chamomile with L-theanine (CTT) beverage, which contains 480 mg of chamomile extract and 200 mg of L-theanine.

Chamomile

Dietary Supplement

A chamomile-flavored beverage

Other names: Chamomile flavored beverage

Primary outcomes

  1. Pain intensity

    Time frame: 2 months

    The pain intensity is assessed using the Visual Analogue Scale (VAS) and the Numeric Rating Scale (NRS). Participants mark the point on the scale (0 to 10) that best represents the average intensity of their menstrual pain. A higher score on the VAS and NRS indicates greater pain intensity.

  2. Menstrual symptoms

    Time frame: 2 months

    The Cox Menstrual Symptom Scale (CMSS) is used to assess the severity of menstrual-related symptoms experienced by participants during their most recent menstrual cycle. Each item in the CMSS is rated on a scale from 0 (not noticeable), 1 (slightly bothersome), 2 (moderately bothersome), 3 (severely bothersome), to 4 (very severely bothersome).

  3. Sleep quality

    Time frame: 2 months

    The Pittsburgh Sleep Quality Index (PSQI) is used to assess the sleep quality of participants during the past week. The total PSQI score ranges from 0 to 21, with higher scores indicating poorer sleep quality.

  4. Mood

    Time frame: 2 months

    The Profile of Mood States (POMS) is used to assess six mood subscales (vigor, tension, depression, anger, fatigue, and confusion) of participants during the past week. Each item is rated on a 5-point Likert scale, ranging from 0 (not at all), 1 (a little), 2 (moderately), 3 (quite a lot), and 4 (extremely).

Secondary outcomes

  1. Hemoglobin

    Time frame: 2 months

    Hemoglobin is measured in mmol/L

Study contacts

Contact information is provided by the study sponsor or research team.

Chin Xuan Tan, PhD

CONTACT

[email protected]

+605-4688888 ext. 4529

Sponsors and collaborators

Lead sponsor

Universiti Tunku Abdul Rahman

Other

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jul 30, 2025
Registry last updated
Jul 30, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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