Skip to main content
OpenTrials
Completed

NCT Number: NCT01233531

Effects of Cash Transfer for the Prevention of HIV in Young South African Women

Cash transfers to young women for staying in school and its effect on acquiring HIV

Completed

Looking for future studies?

Notify Me

Key information

Conditions

HIV

Age range

13 year–20 year

Sex eligibility

Female

Study type

Interventional

Phase

Phase 3

Primary location

Agincourt

Acornhoek, South Africa

About this study

The overall purpose of this study is to determine whether providing cash transfers to young women and their household, conditional on school attendance, reduces young women's risk of acquiring Human Immunodeficiency Virus (HIV). The overall goal of the Conditional Cash Transfer (CCT) intervention is to reduce structural barriers to education with the goal of increasing school attendance of young women, thereby decreasing their HIV risk.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Female aged 13 to 20 years.
  • Enrolled in grades 8, 9, 10 or 11 at the beginning of the study at schools in the AHDSS study site
  • Intending to continue to live in the study site until the end of the follow-up period.
  • Be willing and able to consent/assent to all study procedures including HIV and HSV-2 testing.
  • Able to read sufficiently to use ACASI.
  • Have a bank or post office account or have documentation to be able to open a bank or post office account (i.e., birth certificate, South African National Identification Book, or passport and proof of residence). Post Office accounts will only be required for participants in the Intervention arm.
  • Parent/Legal Guardian who lives with young woman, willing and able to consent to all study procedures including HIV and HSV-2 testing.
  • Parent/Legal Guardian has a bank or post office account or has documentation to be able to open a bank or post office account (i.e. South African National Identification Book, or passport and proof of residence). Note that the account may be opened in the name of any adult who resides in the household with the young woman.

Exclusion criteria

  • Pregnant by self-report at baseline.
  • Married at baseline.
  • No parent or legal guardian living in household.
  • Any other reason that the staff feels would jeopardize the health or well-being of the participant or staff or would prevent proper conduct of the study.

Treatment and study plan

monthly cash transfer payments for attending school

Behavioral

In the intervention, young women and their households will be randomized in 1:1 ratio to receive monthly cash transfer payments, conditional on the young woman attending school, or to the control arm. Young women will be recruited at the beginning of grades 8 through 11 in the first year of the study.

B--No cash transfers

Behavioral

No monthly cash transfers

Primary outcomes

  1. HIV Incidence

    Time frame: 4 years

    To determine whether young women who are randomized to receive CCTs conditional on school attendance have a lower incidence of HIV infection over time compared to young women who are not randomized to receive cash transfers.

Secondary outcomes

  1. HSV-2 incidence

    Time frame: 4 years

    To determine whether young women who are randomized to receive CCTs conditional on school attendance have a lower incidence of Herpes Simplex Virus type 2 (HSV-2) infections over time compared to young women who are not randomized to receive cash transfers.

  2. HSV Incidence

    Time frame: 4 years

    To determine whether young women who receive the CCTs report less unprotected sex, fewer number of sexual partners, younger male partners, an older age of coital debut, a lower incidence of self-reported pregnancy, and greater school attendance compared to young women who do not receive the cash transfers.

Sponsors and collaborators

Lead sponsor

HIV Prevention Trials Network

Network

Collaborators

  • National Institute of Allergy and Infectious Diseases (NIAID)
  • National Institute of Mental Health (NIMH)
  • National Institutes of Health (NIH)

Registry information

Important dates

Study start
2011
Primary completion
2015
Study completion
2015
First posted
Nov 3, 2010
Registry last updated
Mar 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.