Effects of Carnipure® Tartrate on Postprandial Endothelial Function and Recovery

Inclusion criteria

• Healthy men and women between 25 and 45 years
• Body mass index (BMI) between 20 and 30 kg/m²
• Non-smoker
• Physically active 1-2 times per week

Exclusion criteria

• Competitive athlete or performance of high intensity training
• Vegan
• Nutrition with high portion of meat (> 3 times meat per week).
• Injury at the finger
• History or presence of significant cardiovascular disease or co-morbidities (i.e., diabetes, etc.)
• Known allergy to ingredients of study preparation
• Disturbed absorption due to changes in the gastrointestinal tract (e.g., resections, diverticula, blind-loop syndrome)
• Hypo/ hypertension or taking anti hypo/ hypertension medication
• Untreated thyroid dysfunction
• Atherosclerosis or other relevant musculoskeletal diseases/ injuries
• Anemia (women: Hb <11 g/ dl; men: 12.5 g/ dl)
• Eating disorder
• Present or recent use of drugs and dietary supplements that affect the endothelial function, re-covery or lipid status 2 months before or during the study (e.g. L-Carnitine, Arginine, omega3 FA, polyphenol rich supplements (e.g. OPC, cacao, etc) antihypertensive drugs, anti hyperlipidemic drugs, regular intake of protein-shakes etc.)
• Subjects not willing to abstain from intake of analgesic medication 24 hours prior to and during visit 1b and 3b.
• Female patients that are pregnant or nursing
• Night shift worker
• Donation of blood or similar blood loss within the previous 30 days before screening;
• Participation in a clinical trial with an investigational product within 30 days before screening
• Known alcohol abuse or drug abuse
• Known infection of human immunodeficiency virus (HIV) or hepatitis B or C
• Known lactose intolerance, dairy protein allergy or allergy to nuts