Skip to main content
OpenTrials
Completed

NCT Number: NCT03370081

Effects of Capnometry Monitoring in Post Anesthesia Care Unit

There is few information about the best capnometry value in recovery room for intubated awakening patients. Furthermore, capnometry values could influence ventilation applied by nurses on these patients. The aim of this study is to observe the effects of capnometry monitoring on intubated awakening patients in recovery room.

Completed

Looking for future studies?

Notify Me

Key information

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Centre hospitalier Universitaire de Bordeaux

Bordeaux, 33076, France

About this study

In France, there is actually no recommandation about capnography monitoring in recovery rooms. Nevertheless, some patients are still ventilated in post-anesthesia care units during awakening period. Alveolar hypoventilation could induce moderate hypercapnia, thereby stimulate central ventilatory command. However, this hypoventilation could delay the clearance of anesthetic gases. Capnometry monitoring could influence ventilation applied to these patients. Recovery rooms nurses would perform moderate hyperventilation in response to hign capnometry values. This method could enhance gases elimination, with faster spontaneous breathing recovery and extubation. Length of stay in recovery room could also be shortened. An objective surrogate of ventilation is maximal End Tidal CO2, if there is no alveolo-capillary gradient abnormality (Obesity, Chronic respiratory disease, Cyanogenic heart disease). Thus, this study will compare the percentage of patients who reached a maximum End Tidal CO2 greater than 45mmHg during awakening period in post-anesthesia care unit (PACU) in 2 groups :

  • first group ("non-blind group") with capnography monitoring see by the PACU nurses
  • second group ("blind group") with capnography monitoring but PACU nurses cannot see the values Other parameters like the time between ventilator's disconnection and the first ventilatory cycle in spontaneous ventilation, the time between ventilator's disconnection and tracheal extubation or laryngeal mask's withdrawal, the minimal SpO2 reached after tracheal extubation or laryngeal mask withdrawal or the length of stay in PACU are also recorded.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Major patients with given written consent
  • General anesthesia, induction with Propofol infusion and Target-Controlled Infusion (TCI) remifentanil, relayed with inhaled sevoflurane and TCI remifentanil
  • Upper airway control with naso-orotracheal tube or laryngeal mask
  • Ventilated normotherm patients in PACU

Exclusion criteria

  • Minor or pregnant patients
  • Obesity with Body Mass Index > 40 kg/m²
  • Chronic respiratory disease with SpO2<90% in ambiant air
  • Cyanogenic heart disease
  • Patients under myorelaxant in PACU

Treatment and study plan

CAPNOGRAPHY

Device

MONITORING OF CAPNOMETRY USING ETCO2 METHOD

Primary outcomes

  1. End Tidal CO2 up

    Time frame: through awakening period in PACU, an average of 30 minutes

    Percentage of patients who reached a maximum End Tidal CO2 greater than 45mmHg during awakening period in post-anesthesia care unit (PACU)

Secondary outcomes

  1. End Tidal CO2 max 1

    Time frame: through awakening period in PACU, an average of 15 minutes

    Maximum EtCO2 reached before the first ventilatory cycle in spontaneaous ventilation

  2. End Tidal CO2 max 2

    Time frame: through awakening period in PACU, an average of 30 minutes

    Maximum EtCO2 reached after the first ventilatory cycle in spontaneous ventilation

  3. respiratory rate

    Time frame: through awakening period in PACU, an average of 15 minutes

    Respiratory rate applied by PACU nurse before the first ventilatory cycle in spontaneous ventilation

  4. spontaneous ventilation time

    Time frame: through awakening period in PACU, an average of 15 minutes

    Time (in minutes) between ventilator's disconnection and the first ventilatory cycle in spontaneous ventilation

  5. time for removal of airway device

    Time frame: through awakening period in PACU, an average of 30 minutes

    Time (in minutes) between ventilator's disconnection and tracheal extubation or laryngeal mask's withdrawal

  6. Spo2 min

    Time frame: through awakening period in PACU, an average of 2 hours

    Minimal SpO2 after tracheal extubation or laryngeal mask withdrawal

  7. length of stay in PACU

    Time frame: through awakening period in PACU, an average of 2 hours

    Length of stay in PACU in minutes

  8. time for oxygenotherapy removal

    Time frame: through awakening period in PACU, an average of 1 hour

    Time (in minutes) between tracheal extubation or laryngeal mask withdrawal and oxygenotherapy weaning

Sponsors and collaborators

Lead sponsor

University Hospital, Bordeaux

Other

Registry information

Acronym: CAPNOSSPI

Important dates

Study start
2018
Primary completion
2018
Study completion
2018
First posted
Dec 12, 2017
Registry last updated
Oct 16, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.