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NCT Number: NCT07182812

Effects of Blood Flow Restriction Exercises on Lumbar Muscle Endurance and Balance in Healthy Young Adults

This study aims to examine the effects of blood flow restriction (BFR) exercises on back muscle endurance and balance in healthy young adults. BFR is a training method that involves applying controlled pressure to the limbs with a cuff while performing simple exercises. It has been shown to improve muscle strength and endurance even at low exercise loads, reducing stress on the joints.

In this study, participants aged 20 to 25 years will be randomly assigned to two groups. One group will perform sit-to-stand (STS) exercises combined with BFR, while the other group will perform the same exercises without BFR. The exercise program will last 6 weeks, with 2 sessions per week.

Before and after the program, participants will be assessed for:

Lumbar extensor muscle endurance (using the Biering-Sørensen test)

Balance performance (using a computerized balance platform)

Physiological responses such as oxygen saturation, heart rate, and blood pressure

The purpose of this research is to determine whether BFR exercises improve spinal muscle endurance and balance more effectively than standard sit-to-stand exercises. The results may provide new insights into the use of BFR training as a safe and practical strategy for improving posture, preventing back problems, and enhancing physical performance in young adults.

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Key information

Age range

20 year–25 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Selçuk University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation

Konya, 42130, Turkey (Türkiye)

Location contact

Mehmet Akif Güler, PhD, PT

CONTACT

[email protected]

+90 542 464 42 09

About this study

Detailed Description:

Low back muscle endurance and postural balance are essential components of physical health, functional capacity, and injury prevention. Weakness or fatigue in lumbar extensor muscles is associated with spinal instability, poor posture, and an increased risk of low back pain. Similarly, reduced balance control may impair daily activities and athletic performance. Sedentary lifestyles and prolonged sitting are known to negatively affect these functions in young adults.

Blood flow restriction (BFR) training is an innovative exercise method in which a cuff is applied to partially restrict blood flow in the exercising limb during low-load resistance or functional exercises. This technique has been shown to enhance muscle strength, hypertrophy, and endurance with relatively low mechanical stress, thereby reducing the potential risks associated with high-intensity training. While BFR has been studied extensively in the context of lower-limb strength training, its effects on spinal musculature and balance performance are not well understood.

The present randomized controlled trial is designed to investigate the effects of BFR applied during sit-to-stand (STS) exercises on lumbar extensor muscle endurance and balance performance in healthy young adults. Participants will be randomly assigned to one of two groups:

BFR Exercise Group: STS exercises performed with BFR applied to the thigh.

Control Group: STS exercises performed without BFR.

The intervention will last six weeks, with two supervised exercise sessions per week. The BFR cuff pressure will be set at 60-80% of the individual's systolic blood pressure and monitored to ensure participant safety.

Assessments will be conducted at baseline and after the six-week training program. The primary outcomes are lumbar extensor endurance, measured with the Biering-Sørensen test, and postural balance, assessed using a computerized balance platform. Secondary outcomes include oxygen saturation, heart rate, and blood pressure responses before and after exercise sessions.

The study hypothesizes that participants in the BFR exercise group will show greater improvements in lumbar muscle endurance and balance compared to the control group. Findings from this trial will help clarify whether BFR-based functional training can be considered a safe and effective method not only for enhancing muscle performance but also for improving postural stability in healthy individuals. This may have future applications in sports performance, preventive strategies for low back disorders, and rehabilitation programs for populations with musculoskeletal impairments.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age between 20 and 25 years
  • Healthy, without musculoskeletal disorders
  • No chronic neurological or systemic disease
  • No regular exercise program in the last 3 months
  • Voluntary participation with signed informed consent

Exclusion criteria

  • History of musculoskeletal disease, injury, or chronic low back pain
  • Neurological conditions or regular use of medications affecting balance or cardiovascular function
  • Pregnancy
  • Participation in regular lumbar or core exercise programs within the last 3 months
  • Any symptoms during exercise (e.g., excessive fatigue, dizziness, abnormal blood pressure changes) that may pose health risks
  • Withdrawal of consent or inability to comply with study protocol

Treatment and study plan

Blood Flow Restriction Sit-to-Stand Exercise

Behavioral

Participants perform sit-to-stand (STS) exercises with blood flow restriction applied using a pneumatic cuff placed on the thigh. Cuff pressure is set at 60-80% of the participant's systolic blood pressure. Sessions are supervised by a physiotherapist twice per week for six weeks.

Sit-to-Stand Exercise without Blood Flow Restriction

Behavioral

Participants perform the same sit-to-stand (STS) exercise protocol as the experimental group, but without blood flow restriction. Sessions are supervised twice weekly for six weeks, and outcomes are assessed before and after the program.

Primary outcomes

  1. Lumbar Extensor Muscle Endurance

    Time frame: Baseline and after 6 weeks of intervention

    Endurance of the lumbar extensor muscles will be assessed using the Biering-Sørensen Test. Participants maintain the upper body in a horizontal position while lying prone with the pelvis stabilized. The test duration (in seconds) until trunk decline >5-10° will be recorded.

  2. Postural Balance Performance

    Time frame: Baseline and after 6 weeks of intervention

    Balance performance will be evaluated using a computerized balance platform (TechnoBody™ Pro-Kin). Both static and dynamic balance parameters will be recorded. Outcome measures include sway area (cm²), sway velocity (cm/s), and postural stability index.

Secondary outcomes

  1. Change in Oxygen Saturation

    Time frame: Baseline and immediately after exercise sessions (pre- and post-intervention at 6 weeks)

    Peripheral oxygen saturation (SpO₂, %) will be measured using a pulse oximeter placed on the finger. Measurements will be taken before and after exercise sessions, and changes from baseline to week 6 will be recorded.

  2. Change in Blood Pressure

    Time frame: Baseline and immediately after exercise sessions (pre- and post-intervention at 6 weeks)

    Systolic and diastolic blood pressure will be measured using a validated digital sphygmomanometer. Measurements will be taken at rest before and after exercise sessions. The change from baseline to week 6 will be compared between groups.

  3. Change in Body Mass Index (BMI)

    Time frame: Baseline and after 6 weeks of intervention

    Body mass index (kg/m²) will be calculated from height and weight measured with a digital body composition analyzer (Tanita device). Changes from baseline to week 6 will be analyzed.

Study contacts

Contact information is provided by the study sponsor or research team.

Mehmet Akif Güler, PhD, PT

CONTACT

[email protected]

+90 542 464 42 09

Sponsors and collaborators

Lead sponsor

Mehmet Akif Guler

Other

Collaborators

  • The Scientific and Technological Research Council of Turkey

Registry information

Official study title

Effects of Blood Flow Restriction Sit-to-Stand Exercises on Lumbar Extensor Muscle Endurance, Balance, and Physiological Parameters in Healthy Young Adults: A Randomized Controlled Trial

Acronym: BFR-LUMBEX

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Sep 19, 2025
Registry last updated
Sep 19, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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