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OpenTrials
Completed

NCT Number: NCT01213719

Effects of Betaine Supplementation on Strength and Muscle Creatine Content

It has been suggested that betaine supplementation may improve muscle strength by increasing muscle creatine content. However, there is no data supporting this assumption. The investigators speculate that betaine supplementation could enhance intramuscular creatine content, which would result in strength improvements.

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Key information

Conditions

Healthy Subjects

Age range

18 year–30 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

University of Sao Paulo

São Paulo, 05508-030, Brazil

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • physically inactive
  • non-obese

Exclusion criteria

  • skeletal muscle disturbance
  • cardiovascular disturbance
  • use of dietary supplements

Treatment and study plan

Creatine

Dietary Supplement

20g/d throughout 10 days

Betaine

Dietary Supplement

2g/d throughout 10 days

DEXTROSE

Dietary Supplement

dextrose (placebo), 20 g/d throughout 10 days

creatine plus betaine

Dietary Supplement

creatine (20g/d) plus betaine (2g/d) throughout 10 days

Primary outcomes

  1. strength

    Time frame: after 10 days

Secondary outcomes

  1. intramuscular creatine content

    Time frame: after 10 days

Sponsors and collaborators

Lead sponsor

University of Sao Paulo

Other

Registry information

Official study title

Effects of Betaine Supplementation Combined or Not With Creatine Supplementation on Muscle Creatine Content and Strength

Important dates

Study start
2010
Primary completion
2011
Study completion
2011
First posted
Oct 4, 2010
Registry last updated
Jan 16, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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