School and Graduate Institute of Physical Therapy, National Taiwan University
Taipei, 100, Taiwan
NCT Number: NCT04364152
Walking deficits and altered brain capacity have been proved to be two of the main contributing factors in dual-task walking deficits in patients with Parkinson's disease (PD). In the past, patients with PD were usually suggested not to walk in dual-task conditions in order to concentrate on their walking performance better. However, since dual-task walking is really common in daily-life, this limitation usually lead to a decrease in quality of life for PD patients. In previous studies, effects of using attentional strategies in dual-task walking training remain unclear, while suitable attentional strategies and corresponded neuroplasticity for patients with and without freezing of gait have not been well discussed, either. Accordingly, this study is aimed to identify (1) whether internal or external attentional strategies is more ideal for PD patients with and without freezing of gait in dual-task walking training, and (2) changes in brain activity after receiving dual-task walking training with different attentional strategies in patients with or without freezing of gait. Our hypothesis are (1) patients with or without freezing of gait will react differently in dual-gait training with different attentional strategies, and (2) changes in brain activities will be different according to different attentional strategies given in the training.
Looking for future studies?
Notify Me40 year and older
All sexes
Interventional
Not applicable
Taipei, 100, Taiwan
The hypothesis will be tested by gait performance, suprapostural tasks performance, relative power spectrum of EEG, and scales including MDS-UPDRS, ABC, BBS, and TUG.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
for PD patients:
for healthy elders:
Exclusion criteria
for PD patients:
Participants will be instructed to perform both motor and cognitive dual-task walking during exercise training. For example, for motor dual-task walking, the participants may be instructed to throw and catch a ball while walking. As for cognitive dual-task walking, the participants may be instructed to name animals or perform calculation while walking.
Time frame: 60 minutes
gait performance
Time frame: 60 minutes
gait performance
Time frame: 60 minutes
gait performance
Time frame: 60 minutes
gait performance
Time frame: 25 minutes
motor suprapostural task performance
Time frame: 25 minutes
motor suprapostural task performance
Time frame: 25 minutes
motor suprapostural task performance
Time frame: 25 minutes
cognitive suprapostural task performance
Time frame: 60 minutes
brain activity under single, motor dual-task, and cognitive dual-task walking conditions
Time frame: 60 minutes
brain activity under single, motor dual-task, and cognitive dual-task walking conditions
Time frame: 60 minutes
brain activity under single, motor dual-task, and cognitive dual-task walking conditions
Time frame: 60 minutes
brain activity under single, motor dual-task, and cognitive dual-task walking conditions
Time frame: 60 minutes
brain activity under single, motor dual-task, and cognitive dual-task walking conditions
National Taiwan University Hospital
Other
Effects of Attentional Focus Strategy on Dual-task Walking Training in Parkinson's Disease With and Without Freezing of Gait
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT06133283
Basal Ganglia Diseases, Brain Diseases
San Antonio, Texas, United States
View Trial DetailsNCT05766813
Basal Ganglia Diseases, Brain Diseases
Phoenix, Arizona, United States
View Trial DetailsNCT07723027
Basal Ganglia Diseases, Brain Diseases
Shakargarh, Punjab Province, Pakistan
View Trial DetailsNCT07361250
Basal Ganglia Diseases, Brain Diseases
Wuhan, Hubei, China
View Trial Details