Skip to main content
OpenTrials
Completed

NCT Number: NCT06790901

Effects of Anesthesia on Atelectasis

We know that respiratory functions of patients are affected under general anaesthesia. Although there are many underlying causes of ventilation-perfusion mismatch in the airways, the main cause is atelectasis during general anaesthesia.

Atelectasis occurs in almost all patients receiving general anaesthesia. The main cause of atelectasis is the loss of muscle tone during general anaesthesia. Postoperative atelectasis was described in the last century. It is defined as the closure of the alveoli due to a decrease in inspiratory force and collapse of the lung and the resulting loss of aeration.

Inhalation anaesthetics have been shown to cause hypoxic pulmonary vasoconstriction in studies. However, not all inhalation anaesthetics affect the airways in the same way.

In patients who will undergo surgical procedures under different general anaesthesia maintenance methods, conditions that disrupt the ventilation-perfusion balance in the lung peroperatively can be diagnosed and monitored early, easily and inexpensively by lung ultrasonography.

Lung ultrasound is a noninvasive, reliable, reliable, radiation-free imaging method that provides instantaneous imaging at the bedside. Lung ultrasound score is a scoring system that provides scoring of the loss of ventilation in the lung. For this purpose, it was aimed to divide both lung tissues into 12 areas and to give a score between 0 and 3 points and to show the severity of the loss of aeration according to the resulting total score.

Completed

Looking for future studies?

Notify Me

Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Zonguladk Bulent ecevit University

Zonguldak, Kozlu, 67600, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18-65 years old ASA I-II Surgical procedure time between 2 hours and 5 hours in supine position Patients who will undergo rhinoplasty, septorhinoplasty operation Patients whose consent was obtained with an informed consent form

Exclusion criteria

  • Those with a history of malignant hyperthermia,
  • People with alcohol or drug addiction,
  • Presence of dementia or confusion,
  • Uncooperative patients,
  • Those with respiratory disease,
  • Those with coronary artery disease, congestive heart failure,
  • Patients with unstable blood pressure,
  • Significant anaemia, liver or kidney disease,
  • Women during pregnancy or lactation,
  • Allergy to anaesthetic agents,
  • Body mass index (BMI) >30 kg/m2,
  • Those with sepsis or bacterial infection, Body temperature below 35°C and above 38°C at control value

Treatment and study plan

Lung ultrasound

Procedure

Determination of atelectsis By Lung Ultrasound Score

Primary outcomes

  1. Peroperative Atelectasis

    Time frame: from induction to postoperative 1st hour

Sponsors and collaborators

Lead sponsor

Zonguldak Bulent Ecevit University

Other

Registry information

Official study title

EVALUATION of PEROPERATIVE ATELECTASIS with LUNG ULTRASOUND SCORE in GENERAL ANAESTHESIA MAINTENANCE METHODS

Important dates

Study start
2023
Primary completion
2024
Study completion
2025
First posted
Jan 24, 2025
Registry last updated
Jan 24, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.