Istanbul Medipol University, Faculty of Physiotherapy and Rehabilitation
Istanbul, Beykoz, 34810, Turkey (Türkiye)
NCT Number: NCT07540936
Bronchiectasis is a chronic lung disease characterized by persistent cough, sputum production, shortness of breath, and recurrent infections, which can reduce physical capacity and quality of life. Non-pharmacological interventions, such as exercise-based approaches, are increasingly used to support symptom management in these patients.
This study aimed to evaluate the effects of an eight-week online yoga program on exercise capacity, dyspnea severity, respiratory function, and quality of life in adults with non-cystic fibrosis bronchiectasis. A total of 70 participants were randomly assigned to either a yoga intervention group or a control group. The yoga group participated in supervised online sessions three times per week, including breathing exercises, postures, and relaxation techniques, while the control group received usual care without additional intervention.
Outcomes were assessed at baseline and after eight weeks using pulmonary function tests, the six-minute walk test (6MWT), the Modified Medical Research Council (mMRC) Dyspnea Scale, and the St. George's Respiratory Questionnaire (SGRQ). The study investigated whether yoga could provide a safe and effective complementary approach to improve symptoms and functional capacity in individuals with bronchiectasis.
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Notify Me30 year–55 year
All sexes
Interventional
Not applicable
Istanbul, Beykoz, 34810, Turkey (Türkiye)
Bronchiectasis is a chronic and progressive respiratory disorder characterized by irreversible bronchial dilatation, chronic airway inflammation, and recurrent infections. Patients commonly experience dyspnea, reduced exercise tolerance, fatigue, and impaired quality of life. In addition to pharmacological treatments, pulmonary rehabilitation and exercise-based interventions play an important role in symptom management and functional improvement.
Yoga is a mind-body intervention that integrates breathing exercises (pranayama), physical postures (asanas), and relaxation techniques. Previous studies in chronic respiratory diseases, such as asthma and chronic obstructive pulmonary disease, have demonstrated that yoga can improve respiratory muscle function, ventilatory efficiency, and overall well-being. However, evidence regarding its effectiveness in bronchiectasis remains limited.
This randomized controlled trial was conducted to investigate the effects of an eight-week online yoga program on pulmonary function, functional exercise capacity, dyspnea perception, and disease-specific quality of life in patients with non-cystic fibrosis bronchiectasis. Participants were recruited from the Department of Chest Diseases at Istanbul Medipol University between January 2025 and October 2025. Eligible participants were randomly assigned to either a yoga intervention group or a control group using a computer-generated randomization method.
The intervention consisted of 24 supervised online yoga sessions delivered over eight weeks (three sessions per week). Each session included structured breathing exercises, postural practices, and relaxation techniques designed to improve respiratory control, chest expansion, and physical awareness. The control group received standard care without additional intervention during the study period.
Outcome measures included spirometric parameters (FEV1, FVC, FEV1/FVC, PEF, FEF25-75), functional exercise capacity assessed by the six-minute walk test (6MWT), dyspnea severity measured by the Modified Medical Research Council (mMRC) Dyspnea Scale, and health-related quality of life evaluated using the St. George's Respiratory Questionnaire (SGRQ). Assessments were performed at baseline and after the eight-week intervention period.
The study aimed to determine whether yoga could serve as a safe, feasible, and effective complementary intervention to improve functional outcomes and symptom burden in individuals with bronchiectasis, particularly in the context of accessible and remote rehabilitation models.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
The intervention consisted of an eight-week online supervised yoga program including breathing exercises (pranayama), physical postures (asanas), and relaxation techniques. Sessions were conducted three times per week, totaling 24 sessions. The program was designed to improve respiratory control, chest expansion, and overall physical awareness.
Time frame: Baseline and 8 weeks
The change in functional exercise capacity assessed by the six-minute walk test (6MWT), measured as the distance (in meters) walked in six minutes.
Time frame: Baseline and 8 weeks
Dyspnea severity assessed using the Modified Medical Research Council (mMRC) Dyspnea Scale (0-4), where higher scores indicate greater breathlessness.
Time frame: Baseline and 8 weeks
Disease-specific quality of life assessed using the St. George's Respiratory Questionnaire (SGRQ), including symptom, activity, impact, and total scores (0-100 scale, higher scores indicate worse quality of life).
Time frame: Baseline and 8 weeks
Forced Expiratory Volume in 1 Second (FEV1), Pulmonary function assessed as forced expiratory volume in one second (FEV1) using spirometry.
Time frame: Baseline and 8 weeks
Forced Vital Capacity (FVC), Pulmonary function assessed as forced vital capacity (FVC) using spirometry.
Time frame: Baseline and 8 weeks
FEV1/FVC Ratio, Pulmonary function assessed as the ratio of FEV1 to FVC using spirometry.
Time frame: Baseline and 8 weeks
Peak Expiratory Flow (PEF), Pulmonary function assessed as peak expiratory flow (PEF) using spirometry.
Time frame: Baseline and 8 weeks
Forced Expiratory Flow (FEF25-75), Pulmonary function assessed as forced expiratory flow between 25% and 75% of FVC (FEF25-75) using spirometry.
Istanbul Medipol University Hospital
Other
Effects of an Eight-Week Online Yoga Program on Pulmonary Function, Exercise Capacity, Dyspnea, and Quality of Life in Patients With Non-Cystic Fibrosis Bronchiectasis: A Randomized Controlled Trial
Acronym: YOGA-BR
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