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Completed

NCT Number: NCT00000261

Effects of Alcohol History on Effects of Sevoflurane and Nitrous Oxide - 13

The purpose of this study is to evaluate the effects of alcohol history on the subjective and reinforcing effects of sevoflurane and nitrous oxide in healthy volunteers. All subjects underwent psychomotor testing during 4 sessions of placebo, drug/placebo, and choice of intervention.

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Key information

Conditions

Alcohol-Related Disorders Chemically-Induced Disorders Mental Disorders Narcotic-Related Disorders Opioid-Related Disorders Substance-Related Disorders

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

University of Chicago, Anesthesia & Critical Care

Chicago, Illinois, 60637, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Please contact site for information.

Treatment and study plan

30% Nitrous oxide

Drug

Placebo

Other

No drug (100% oxygen)

0.2% sevoflurane

Drug

0.4% Sevoflurane

Drug

0.6% Sevoflurane

Drug

Primary outcomes

  1. Mood

    Time frame: Baseline, inhalation, recovery

  2. Psychomotor performance

    Time frame: Baseline, inhalation, recovery

  3. Choice of drug vs placebo

    Time frame: After placebo and drug in each session

Sponsors and collaborators

Lead sponsor

University of Chicago

Other

Collaborators

  • National Institute on Drug Abuse (NIDA)

Registry information

Official study title

Effects of Alcohol History on Effects of Sevoflurane and Nitrous Oxide

Important dates

Study start
1997
Primary completion
1998
Study completion
1998
First posted
Sep 21, 1999
Registry last updated
May 27, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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