Effects of Acute Sugar Intake on Choroidal Thickness

This investigation will be a prospective, repeated-measures study. All subjects will arrive fasted and will be asked not to consume any outside food or beverages during the three-hour study period, and will be asked to abstain from caffeine intake for 12 hours before participation. A baseline OCT scan of the macula of the right eye will be performed using the Heidelberg Spectralis OCT system. Participants will then consume 30 grams of sugar in the form of glucose tablets. Macular OCT scans of the right eye will be repeated every 30 minutes for 3 hours following sugar consumption.

Inclusion criteria

• In order to be eligible for enrolment, each subject must have less than 6 diopters of spherical equivalent refractive error, and have no existing diagnosis of diabetes or pre-diabetes.

Exclusion criteria

• Any potential subject with known retinal pathology will be excluded. Any potential subject with any other known systemic or ocular conditions that may impact their ability to participate in the study or provide generalizable data will also be excluded.