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Completed

NCT Number: NCT02999581

Effects of a Pre-Workout Dietary Supplement on Training Adaptations

The purpose of this study is to examine the effects of a pre-workout dietary supplement during resistance training on training adaptations.

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Key information

Age range

18 year–40 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

About this study

A number of nutritional strategies have been developed to optimize nutrient delivery prior to exercise. This includes providing carbohydrate and a number of ergogenic nutrients prior to, during and/or following exercise. As a result, a number of pre-workout supplements have been developed to increase energy availability, promote vasodilation and/or positively affect exercise capacity. The purpose of this study is to investigate the effects of ingesting a pre-workout dietary supplement during resistance training on training adaptations.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • you are an apparently healthy and recreationally active male between the ages of 18 and 40.
  • you will need to have at least six months immediate prior history of resistance training on the bench press and leg press or squat.

Exclusion criteria

  • you have a history of treatment for metabolic disease (i.e., diabetes), hypertension, hypotension, thyroid disease, arrhythmia and/or cardiovascular disease;
  • you are currently using prescription medications;
  • you have an intolerance to caffeine and/or other natural stimulants;
  • you have a history of smoking;
  • you drink excessively (i.e., 12 drinks per week or more);

Treatment and study plan

C4 Extreme, C4 Extreme (without Advantra Z)

Dietary Supplement

Primary outcomes

  1. Examine the effects of C4 supplementation during resistance training by assessing body water

    Time frame: Eight weeks

  2. Examine the effects of C4 supplementation during resistance training by assessing body composition

    Time frame: Eight weeks

  3. Examine the effects of C4 supplementation during resistance training by assessing macronutrient intake

    Time frame: Eight weeks

  4. Examine the effects of C4 supplementation during resistance training by assessing 1 RM (repetition maximum) strength

    Time frame: Eight weeks

  5. Examine the effects of C4 supplementation during resistance training by assessing anaerobic sprint capacity

    Time frame: Eight weeks

  6. Examine the effects of C4 supplementation during resistance training by assessing muscle creatine levels

    Time frame: Eight weeks

  7. Examine the effects of C4 supplementation during resistance training by assessing muscle carnosine levels

    Time frame: Eight weeks

  8. Examine the effects of C4 supplementation during resistance training by assessing cognitive function (i.e., Stroop Color and Word Test, Word Recall Test and Readiness to perform VAS)

    Time frame: Eight weeks

Secondary outcomes

  1. Measure standard clinical chemistry panels in the blood to evaluate safety

    Time frame: Eight weeks

  2. Record side effects to evaluate safety

    Time frame: Eight weeks

  3. Measure heart rate to evaluate safety

    Time frame: Eight weeks

  4. Measure blood pressure to evaluate safety

    Time frame: Eight weeks

Sponsors and collaborators

Lead sponsor

Texas A&M University

Other

Collaborators

  • Nutrabolt

Registry information

Official study title

Effects of a Pre-Workout Dietary Supplement on Training Adaptations in Resistance Trained Athletes

Acronym: NB2

Important dates

Study start
2014
Primary completion
2014
Study completion
2014
First posted
Dec 21, 2016
Registry last updated
Dec 21, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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