Health department
Bali, Kebon Padangan, Indonesia
NCT Number: NCT03956992
The aim of this pilot study is to analyze if a hydroxyapatite-containing mouth gel has an influence on the calcium content of plaque.
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Notify Me7 year–11 year
All sexes
Interventional
Not applicable
Bali, Kebon Padangan, Indonesia
>= 20 subjects (7-11 years) use the hydroxyapatite-containing mouth gel for 3 days (3x per day); without using any other oral care product at this time. A dentist applies the gel on all teeth. At baseline and after 3 days plaque will be collected from buccal and labial surfaces (except surfaces with tartar). A "split-mouth" concept will be used:
Subjects in group A:
Baseline plaque collection: quadrant 1 and 4 Plaque collection after 3 days: quadrant 2 and 3
Subjects in group B:
Baseline plaque collection: quadrant 2 and 3 Plaque collection after 3 days: quadrant 1 and 4 (The time between last application of the gel and plaque collection will be 1 h) The plaque will be dried and afterwards the calcium content of the plaque will be quantitively analyzed by atomic absorption spectroscopy (AAS).
For all subjects: Calcium contents of plaque at baseline and after 3 days application will be compared by statistical methods.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Stop using the mouth gel
Time frame: 3 days
Analysis by atomic absorption spectroscopy (AAS)
Dr. Joachim Enax
Industry
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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