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OpenTrials
Completed

NCT Number: NCT01377493

Effects of a Chewing Gum Containing POs-Ca and Fluoride on Enamel

There were no differences in the degree of enamel remineralization of subsurface lesions among the chewing gums containing or not containing POs-Ca and fluoride.

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Key information

Conditions

Enamel Subsurface Lesion

Age range

20 year–31 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Early Phase 1

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy adult subjects
  • More than 22 permanent teeth

Exclusion criteria

  • Alcohol addiction
  • Smoking
  • Active caries
  • Periodontal pockets
  • Low-saliva flow (less than 0.3ml/min)

Treatment and study plan

chewing gum

Dietary Supplement

chewing gum containing no active ingredients, or Ca-P bioavailable ions, or Ca-P and F bioavailable ions

Primary outcomes

  1. Mineral content of enamel

    Time frame: 2 weeks

    Mineral content of bovine enamel blocks inserted into the subject mouth during chewing of the gums was assessed.

Sponsors and collaborators

Lead sponsor

Tokyo Medical and Dental University

Other

Registry information

Official study title

Effects of a Chewing Gum Containing POs-Ca and Fluoride on Remineralization of Enamel Subsurface Lesions in Situ

Important dates

Study start
2009
Primary completion
2010
Study completion
2011
First posted
Jun 21, 2011
Registry last updated
Jun 21, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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