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NCT Number: NCT03181906

Effectiveness of Pre-Consultation Medication Reconciliation Service in Reducing Unintentional Medication Discrepancies During Transition of Care From Hospital Discharge to Primary Care Setting

This study evaluates the the effectiveness of pre-consultation Medication Reconciliation Service in reducing unintentional medication discrepancies among patients who discharged from hospital to primary care.

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Key information

Age range

21 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Medication discrepancies during care transition were common. Many factors contribute to the risk of medication discrepancies. Despite medication reconciliation service being practiced in the hospital setting, there was limited knowledge on its effectiveness in the primary care setting. This study aims to evaluate the effectiveness of a pre-consultation medication reconciliation service in reducing medication discrepancies in patients who transit from hospital to primary care. Adult patients who made their first visit to the polyclinics following a recent hospital discharge and were prescribed with 5 or more chronic medications were randomised to 2 groups. Pre-consultation medication reconciliation by a pharmacist was carried out for the intervention group. Outcome was assessed by a different pharmacist who was blinded to the randomised allocation. The control group underwent usual care without a pre-consultation medication reconciliation.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 21 years and older
  • Patient or primary caregiver was able to provide informed consent
  • Patient or primary caregiver was English, Mandarin or Malay speaking
  • Patient was able to self-administer medications, or accompanied by a caregiver who assisted in administering medications
  • Patient was prescribed 5 or more chronic medications
  • The day of the study visit was the first follow-up visit in National Healthcare Group Polyclinics for chronic disease management after recent discharge from a local public hospital

Exclusion criteria

  • Residents of nursing home
  • The day of the study visit was for acute illness consult
  • Unwilling to consent to a 30-day follow-up phone call.

Treatment and study plan

Pre-Consultation Medication Reconciliation

Other

Medication reconciliation service to be done for participants randomised to the intervention group

Primary outcomes

  1. Unintentional medication discrepancies

    Time frame: 1 day

    Any unintentional medication discrepancies after doctor's consultation

Secondary outcomes

  1. Types of medication discrepancies

    Time frame: 1 day

    Type of medication discrepancies, by a validated instrument by Claeys et al, (Claeys C, Neve J, Tulkens PM, Spinewine A. Content Validity and Inter-Rater Reliability of an Instrument to Characterize Unintentional Medication Discrepancies.Drugs & Aging. 2012 July; 29(7): 577-91.)

  2. Causes of medication discrepancies

    Time frame: 1 day

    Causes of medication discrepancies, by a validated instrument by Claeys et al, (Claeys C, Neve J, Tulkens PM, Spinewine A. Content Validity and Inter-Rater Reliability of an Instrument to Characterize Unintentional Medication Discrepancies.Drugs & Aging. 2012 July; 29(7): 577-91.)

  3. Medication adherence

    Time frame: 30 days

    Medication adherence by The 8-item Morisky Medication Adherence Scale

  4. 30-day re-hospitalisation

    Time frame: 30 days

    rate of re-hospitalisation 30 days after the study visit

Sponsors and collaborators

Lead sponsor

National Healthcare Group, Singapore

Other Gov

Registry information

Official study title

Effectiveness of Pre-Consultation Medication Reconciliation Service in Reducing Unintentional Medication Discrepancies During Transition of Care From Hospital Discharge to Primary Care Setting- A Randomised Controlled Trial

Important dates

Study start
2016
Primary completion
2017
Study completion
2017
First posted
Jun 9, 2017
Registry last updated
Jun 9, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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