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OpenTrials
Completed

NCT Number: NCT04800900

Effectiveness of Pharmaceutical Interventions in Hospitalized Patients

The presence of multimorbidities is very common among the elderly, which become major consumers of medicines. The process of prescribing medicines for the elderly should be done with caution, as the use of some medications may present more risks than benefits in this range age. Potentially inappropriate prescribing for the elderly has become a global concern for the promotion of an adequate pharmacotherapy, it becomes essential to be aware of the effectiveness and safety of medicines and the knowledge of which drugs whose risks of serious adverse reactions outweigh the benefit of your referral. In this sense, the present study has aim to evaluate the effectiveness of pharmaceutical interventions in frequency of omission of drugs with proven efficacy for cardiovascular diseases and promotion of treatment prescription inappropriate and polypharmacy. A prospective quasi experimental before and after study will be carried out in elderly patients diagnosed with cardiovascular disease admitted to the Ana Nery hospital, Salvador, Bahia, Brazil. A convenience sample will be collected, the data will be released and revised in a database built in the SPSS software and analyzed in the program statistic R and SPSS. At the end of the study, it is expected a decrease in the frequency of omission of medications and promotion of prescription drugs inappropriate.

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Key information

Conditions

Age range

60 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hospital Ana Nery

Salvador, Estado de Bahia, 40301-155, Brazil

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Clinical diagnosis of cardiovascular disease
  • Discharge after 24 hours

Exclusion criteria

  • Death

Treatment and study plan

Pharmaceutical intervention

Other

A pharmacist will analyse patient's prescription, identify if there is prescribing omission and inappropriated drug prescribed and when necessary will require to doctors deprescribe or introduce or remove prescribed drugs

Primary outcomes

  1. Effectiveness of pharmaceutical interventions measured by proportion of accepted interventions and all interventions

    Time frame: The acceptance of all pharmaceutical interventions related to inappropriate prescribed drugs and omission of prescription during the hospitalization of the patient will be evaluated, through study completion, an average of 1 year

Secondary outcomes

  1. Incidence of polypharmacy in elderly people with cardiovascular diseases measured by prescription containing five or more drugs

    Time frame: First prescription after 24 hours of admission, last prescription and discharge prescription through study completion, an average of 1 year

  2. Incidence of omission of prescription drugs with proven efficacy for cardiovascular diseases measured by the START criteria

    Time frame: First prescription after 24 hours of admission, last prescription and discharge prescription through study completion, an average of 1 year

  3. Incidence of potentially inappropriate drug prescription in elderly people with cardiovascular diseases measured by the Beers criteria

    Time frame: First prescription after 24 hours of admission, last prescription and discharge prescription through study completion, an average of 1 year

Sponsors and collaborators

Lead sponsor

Federal University of Bahia

Other

Registry information

Official study title

Effectiveness of Pharmaceutical Interventions in the Omission of Prescription and Desprescription of Medications in Hospitalized Patients

Acronym: INFAR

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Mar 16, 2021
Registry last updated
Apr 12, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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