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OpenTrials
Completed

NCT Number: NCT01406626

Effectiveness of Peer Navigation to Link Released HIV+ Jail Inmates to HIV Care

This study will implement a peer navigation intervention to improve linkage to and retention in HIV care for inmates released from L.A. county jail into the community.

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Key information

About this study

The proposed study has two Primary Specific Aims:

  • To examine individual-level and structural-level barriers to HIV care after release from jail, using formative semi-structured interviews with ex-inmates, case managers, and HIV care providers; and to use the information we obtain to inform the adaptation and tailoring of an intervention designed to improve linkage with and retention to HIV care for HIV+ ex-inmates (Complete);
  • Using a two-group experimental RCT design, to test the adapted peer navigation intervention condition for HIV+ inmates upon release from jail compared to a usual care condition, and to evaluate the intervention's effectiveness at improving linkage with and retention in HIV care, self-reported ART adherence, and HIV RNA viral load suppression;

The intervention is hypothesized to result in greater linkage to care, a greater proportion completing at least three HIV care visits per year, increased self-reported ART adherence, and decreased levels of HIV RNA viral load compared to the usual care control group.

Secondary Aims of the study include assessing the potential moderating effects of substance abuse, the potential mediating effects of substance abuse treatment, and the program's effects on recidivism, and costs.

Active substance abuse is hypothesized to moderate the effect of the intervention, such that the intervention will be less effective among participants who report substance use.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18 or older
  • Men or TGW diagnosed HIV-positive
  • English or bilingual Spanish speaking
  • Selected for the TCM program (control condition) prior to LINK LA enrollment
  • Residing in LA County upon release
  • Eligible for ART or incarcerated on ART.

Exclusion criteria

  • Inability to give informed consent
  • Parole hold or planned transfer to prison
  • Stay in jail <5 days.

Treatment and study plan

Peer Navigator

Behavioral

Peer navigation intervention to improve linkage to and retention in HIV care and suppress viral load for underserved HIV+ persons in Los Angeles

Primary outcomes

  1. Linkage to HIV Care

    Time frame: 12 months

    Number of HIV+ ex jail inmates accessing HIV care

  2. Retention in Treatment

    Time frame: 12 months

    This assesses whether or not the HIV+ ex jail inmates were retained in their HIV care after first accessing care.

  3. Adherence to Treatment

    Time frame: 12 months

    How adherent the HIV+ ex jail inmates are to their treatment regiment, by self-report.

  4. Viral Load

    Time frame: 12 months

    HIV+ ex jail inmates' viral load

Secondary outcomes

  1. Costs

    Time frame: 12 months

    Cost of the intervention and HIV care

Sponsors and collaborators

Lead sponsor

University of California, Los Angeles

Other

Collaborators

  • Los Angeles County Department of Public Health

Registry information

Acronym: LINK LA

Important dates

Study start
2012
Primary completion
2016
Study completion
2016
First posted
Aug 1, 2011
Registry last updated
Nov 18, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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