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Completed

NCT Number: NCT06320938

Effectiveness of Neuroscience-based Pain Education in Patients With Chronic Neck Pain

The effectiveness of neuroscience-based pain education, myofascial induction technique, and home exercise programs will be compared in patients with chronic neck pain.

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Key information

Conditions

Cervical Spine Disease Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Türkoğlu Dr. Kemal Beyazıt State Hospital

Kahramanmaraş, Turkey (Türkiye)

About this study

The study aims to present the immediate and long-term effects of Neuroscience-based Pain Education (NPE) and Myofascial Induction Therapy (MIT). It will evaluate parameters such as pain, quality of life, pain catastrophizing, and neck disability after treatment completion and at the 6-month follow-up.

The investigators aim to illuminate future studies concerning neuroscience-based pain education, which has gained prominence in recent years and continues to increase in importance annually.

The participants will be randomly assigned to one of three groups:

1 Group: Neuroscience-Based Pain Education Combined with Home Exercise Program Participants in this group will receive Neuroscience-Based Pain Education (NPE) treatment in addition to the home exercise program. Training sessions will be organized as one-on-one conversation sessions focusing on the neurophysiology of pain, and participants will be reinforced through PowerPoint presentations and visual aids such as pictures, templates, and metaphors.

Group: Myofascial Induction Techniques Combined with Home Exercise Program In addition to the home exercise program, Myofascial Induction Techniques (MIT) group participants will have MIT applied to the cervical and upper thoracic regions.

Group: Home Exercise Program After undergoing general training, participants in this group will be taught an exercise program. The program will include neck muscle stretching, strengthening, and posture exercises.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Ages between 18-60 years old,
  • Patients with non-specific neck pain for at least 3 months,
  • Having pain severity of four or more according to the Visual analogue scale (VAS),
  • Patients with Pain Catastrophizing Scale score > 30
  • Patients with a Central Sensitization Inventory score > 30
  • Not having received physiotherapy and manual therapy within the last 3 months,
  • Those who have not received and will not receive medical treatment in the last 3 months.

Exclusion criteria

  • Having a history of neck and spine surgery,
  • Patients with whiplash injury, fracture history,
  • Having unstable neurological findings,
  • Presence of a pathology such as hernia and root compression in the cervical region,
  • Those who regularly use analgesic and anti-inflammatory drugs,
  • A communication problem may prevent the implementation of the evaluations or treatment program.

Treatment and study plan

Neuroscience-Based Pain Education Combined with Home Exercise Program

Other

Neuroscience-Based Pain Education and Home Exercises will be applied.

Myofascial Induction Techniques Combined with Home Exercise Program

Other

Myofascial Induction Techniques and Home Exercises will be applied.

Home Exercises Group

Other

Home Exercises wiil be applied

Primary outcomes

  1. Short Form McGill Pain Questionnaire

    Time frame: Baseline,8 weeks, 6 months

    A short form of the McGill Pain Questionnaire (SF-MPQ) used in pain assessment consists of four sections. In the first section, participants are asked to mark the location of pain on a body diagram. In the second section, participants are asked to select the word that best describes their pain from twenty subgroups. The third section investigates the relationship of pain over time, while the fourth and final section requires participants to indicate the intensity of pain on a scale of 1 to 5 and provide written responses to six questions. The questionnaire is scored from 0 to 112. The higher the pain score, the greater the pain.

  2. Algometric Digital Measurement

    Time frame: Baseline,8 weeks, 6 months

    It is a digital device used to evaluate trigger point sensitivity.

  3. Central Sensitization Inventory

    Time frame: Baseline,8 weeks, 6 months

    The scale, which can be applied in chronic pain, is used in central sensitization syndromes. It consists of two parts. Section A questions health-related symptoms, and part B questions whether any central sensitization syndromes have been diagnosed before.

  4. Head Posture Evaluation

    Time frame: Baseline,8 weeks, 6 months

    Forward head posture is measured with a goniometer, which measures the angle between the horizontal plane and the seventh cervical vertebra and ear line.

  5. Neck Disability Index

    Time frame: Baseline,8 weeks, 6 months

    The scale consists of ten headings in total. It includes neck pain intensity, personal care, lifting, reading, headaches, concentration, driving, sleep, and leisure activities.

  6. Pittsburgh Sleep Quality Index

    Time frame: Baseline,8 weeks, 6 months

    This survey contains 24 questions about sleep status, both during the day and at night. Nineteen of these are to be answered personally, and five are to be answered by a spouse or roommate.

  7. 36-Item Short Form Health Survey Questionnaire

    Time frame: Baseline,8 weeks, 6 months

    36-Item Short Form Health Survey (SF-36) questionnaire consists of eight subscales: physical functioning, social functioning, role limitations due to physical problems, pain, vitality, mental health, and general health perception. Each subscale is scored from 0 to 100, and the scores from these subscales are not summed. A high score indicates good health status.

  8. Pain Catastrophizing Scale

    Time frame: Baseline,8 weeks, 6 months

    The Pain Catastrophizing Scale (PCS) is a 13-item self-report measure of catastrophizing in the context of actual or anticipated pain. The PCS measures catastrophizing as a multidimensional construct with three subscales: rumination, magnification, and helplessness. Rumination focuses on thoughts related to pain, helplessness reflects feelings of helplessness in coping with a painful situation, and magnification is a general view of the threat of pain. High PCS scores are associated with greater pain and more functional impairment. A total score above 30 represents clinically significant levels of pain catastrophizing.

Sponsors and collaborators

Lead sponsor

Turkoglu Dr. Kemal Beyazit State Hospital

Other

Registry information

Official study title

Comparison of the Effects of Neuroscience-Based Pain Education and Myofascial Induction Technique on Pain and Quality of Life in Patients With Chronic Neck Pain

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Mar 20, 2024
Registry last updated
Sep 3, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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