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Completed

NCT Number: NCT01636752

Effectiveness of Internet-based Depression Treatment

Care for people suffering from depressive symptoms should be given in a step-wise approach. One first step can be the provision of self-help material. Online self-help is an innovative way of providing self-help. The investigators want to study the effect of an interactive online self-help-program (Deprexis) in the treatment of mild to moderate depressive symptoms. Participants will be randomised to either twelve weeks of online-self help or a waiting-list control. Symptoms of depression and other aspects will be assessed over a one year period. Thereafter the controls will also receive online-self help. The investigators hypothesise that online self-help is superior to the control condition in alleviating depressive symptoms and preventing full blown depression.

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Key information

Conditions

Mild to Moderate Depressive Symptoms

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Charité Berlin, Berlin, Germany

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About this study

This study is supported by the German Ministry of Health (BMG) and is a collaborative project of Universität Bern (PD Dr. Thomas Berger), Charité Berlin (PD Dr. Matthias Rose), Universität Bielefeld (Prof. Dr. Wolfgang Greiner), Universität Hamburg (Prof. Dr. Steffen Moritz, Prof. Dr. Bernd Löwe), GAIA AG Hamburg (Dr. Björn Meyer), Universität Tübingen (Prof. Dr. Martin Hautzinger) and Universität Trier (Prof. Dr. Wolfgang Lutz).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • PHQ>4 and <15

Exclusion criteria

  • acute suicidality
  • psychotic d/o, bipolar d/o or other severe psychiatric d/o

Treatment and study plan

Deprexis

Behavioral

Online self-help with and without e-mail-support

Primary outcomes

  1. Personal Health Questionnaire (PHQ-9)

    Time frame: 12 wks

Secondary outcomes

  1. Hamilton Rating Scale for Depression (HRSD)

    Time frame: 12 wks, 6 mths, 12 mths

  2. Quick Inventory of Depressive Symptoms (QIDS)

    Time frame: 12 wks, 6 mths, 12 mths

  3. Personal Health Questionnaire (PHQ-9)

    Time frame: 6 mths, 12 mths

Sponsors and collaborators

Lead sponsor

University of Luebeck

Other

Registry information

Acronym: EVIDENT

Important dates

Study start
2012
Primary completion
2015
Study completion
2017
First posted
Jul 10, 2012
Registry last updated
Oct 12, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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