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Completed

NCT Number: NCT02419586

Effectiveness of Gum Chewing on Ileus in Chinese Colorectal Patients Underwent Laparoscopic Colorectal Surgery

Gum chewing group will have less ileus and early resume of bowel motion than control group.

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Key information

Conditions

Colorectal Cancer Colonic Diseases Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Neoplasms Neoplasms by Site Rectal Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Queen Mary Hospital

Hong Kong, China

About this study

The standardize surgical techniques, less used of epidural analgesia, early ambulation and used of naso-gastric tube for decompression are aimed to reduce the paralytic ileus after abdominal surgery . Most Western studies have examined and found that gum chewing are able to prevent postoperative ileus or promotes early bowel function after abdominal surgery.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with newly diagnosed colorectal cancer undergoing laparoscopic resection in in Queen Mary Hospital
  • At least 18 years
  • Speak Cantonese
  • Able to follow study protocol and chewing gum study

Exclusion criteria

  • Cognitive disability
  • Requirement of epidural analgesia
  • Requirement of intensive care unit/ High dependency unit care postoperatively
  • Inability to chew
  • Presence of procedure other than colorectal resection
  • Non Chinese

Treatment and study plan

bubble gum

Other

Chewing gum group patients performing gum chewing on postoperative day 1 at three times daily for 30 minutes after operation and until discharged.

Primary outcomes

  1. Time to first flatus

    Time frame: from postoperative day 0 till an expected average of day 7

    Time to passage of flatus after surgery was significantly shorter in the intervention group (22 vs 39 hours, p=0.007).

Secondary outcomes

  1. Time to first sense of hunger

    Time frame: from postoperative day 0 till an expected average of day 7

    Patients in the intervention group also noticed feeling of hunger earlier (17 vs 40 hours, p<0.001).

  2. Time to first bowel movement,

    Time frame: from postoperative day 0 till an expected average of day 7

    The first bowel motion also occurred earlier in the intervention group (22 vs 52 hours, p<0.001)

  3. Length of stay

    Time frame: from postoperative day 0 till an expected average of day 7

    There is no difference in length of stay between intervention group or control group

Sponsors and collaborators

Lead sponsor

Shum Nga Fan

Other Gov

Registry information

Official study title

Effectiveness of Gum Chewing on Reduction of Postoperative Paralytic Ileus for Chinese Colorectal Cancer Patients Underwent Laparoscopic Colorectal Surgery and Enhanced Recovery Program

Important dates

Study start
2015
Primary completion
2015
Study completion
2016
First posted
Apr 17, 2015
Registry last updated
Jun 21, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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