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Completed

NCT Number: NCT06975449

Effectiveness of Graded Training in the Vivifrail Exercise Program Among Long-Term Care Residents

This study evaluates the effectiveness of the Vivifrail multicomponent physical exercise program among elderly residents with different levels of frailty in long-term care centers. A 12-week intervention will be conducted in randomly assigned experimental and control groups. Outcomes include physical performance, fall risk, grip strength, calf circumference, and ICOPE function.

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Key information

Conditions

Frailty Aging Behavior Pathologic Processes Pathological Conditions, Signs and Symptoms Physical Inactivity Sedentary Behavior

Age range

70 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

China Medical University

Taichung, 406040, Taiwan

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥70, resident in LTC center, ambulatory, physician-cleared for training

Exclusion criteria

  • Conditions listed in Vivifrail exclusion criteria (e.g., acute MI, unstable angina, recent fractures, uncontrolled hypertension, etc.)

Treatment and study plan

Multicomponent Physical Exercise Program (Vivifrail)

Behavioral

Vivifrail physical training, 5 times/week, 50-60 minutes/session for 12 weeks

Primary outcomes

  1. SPPB Score change at Weeks 0, 4, 8, 12, 16, 20, 24

    Time frame: SPPB Score change at Weeks 0, 4, 8, 12, 16, 20, 24

    SPPB Score change at Weeks 0, 4, 8, 12, 16, 20, 24

  2. Fall risk assessment (TUG, gait speed, number of falls) at Weeks 0, 4, 8, 12, 16, 20, 24

    Time frame: Fall risk assessment (TUG, gait speed, number of falls) at Weeks 0, 4, 8, 12, 16, 20, 24

    Fall risk assessment (TUG, gait speed, number of falls) at Weeks 0, 4, 8, 12, 16, 20, 24

Secondary outcomes

  1. ICOPE function assessment at Weeks 0, 12, 24

    Time frame: ICOPE function assessment at Weeks 0, 12, 24

    ICOPE function assessment at Weeks 0, 12, 24

  2. Grip strength (hand dynamometer) at Weeks 0, 12, 24

    Time frame: Grip strength (hand dynamometer) at Weeks 0, 12, 24

    Grip strength (hand dynamometer) at Weeks 0, 12, 24

Sponsors and collaborators

Lead sponsor

China Medical University Hospital

Other

Registry information

Official study title

Effectiveness of Graded Training in the Multicomponent Vivifrail Exercise Program Among Residents of Long-Term Care Facilities: A Randomized Controlled Trial

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
May 16, 2025
Registry last updated
Mar 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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