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NCT Number: NCT07236424

Effectiveness of Exercise, Walking, and Education on Mental Health, Mobility and Quality of Life in Elderly Residents of Nursing Homes

Clinical Trial This clinical trial aims to determine the impact of physiotherapy interventions on mental health, quality of life, and spinal mobility in older adults. The physiotherapy intervention will consist of group exercise therapy (3 times a week, 40 minutes, 4 weeks in total), walking activities (3 times a week, 30 minutes, 4 weeks in total), and education on optimal positions and movements in daily activities (one session lasting 60 minutes)

The main questions it aims to answer are:

1. Are group exercise therapy and walking optimal for reducing symptoms of depression and anxiety and improving quality of life in older adults placed in nursing homes in a short period of time 2. Do physiotherapy interventions improve spinal mobility (anteflexion and extension)?

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Key information

Age range

65 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Nursing home "Ministro", Žepče

Žepče, 72230, Bosnia and Herzegovina

About this study

Population ageing is a worldwide phenomenon resulting from increased living standards, improved healthcare, and decreased birth rates. The proportion of people aged 60 and over continues to grow and is expected to exceed two billion by 2050, with 80% of them living in developed countries.

Ageing is associated with a decline in physical and mental capacities, increased risk of chronic diseases, and social isolation, leading to higher healthcare and social costs. However, many of these challenges can be prevented or mitigated through timely interventions. Global health initiatives promote Healthy and Active Ageing, focusing on maintaining longevity, well-being, and quality of life. Physical activity and exercise therapy are the most effective interventions for promoting physical and mental health, highlighting the essential role of physiotherapy. Physiotherapists are well-positioned to promote healthy ageing due to their accessibility, cost-effectiveness, and expertise in managing a wide range of health conditions. Increasing evidence shows that physiotherapy not only enhances physical function but also contributes significantly to the mental well-being of older adults.

Recent systematic reviews with meta-analyses have reported positive effects of exercise therapy and physical activity on reducing depression, anxiety, and improving quality of life among older adults. An umbrella review reports high benefits of physical activity for improving symptoms of depression, anxiety, and distress across a wide range of adult populations, including the general population, people with diagnosed mental health disorders, and people with chronic disease. A systematic review with meta-analysis confirmed exercise as an effective treatment for anxiety. However, the heterogeneity of the included studies does not provide clearer information about the optimal exercise methods, as well as the necessary parameters and ways of implementing exercise therapy. In addition, individual studies show conflicting results on the effects of physical activity in nursing home residents; one reports benefits of a structured exercise program on depressive symptoms and quality of life, while another finds no significant improvement with supervised moderate aerobic and resistance training.

Thus, this study aim is to determine the optimal methods of exercise therapy and physical activity, as well as other parameters such as frequency, intensity, supervision, and method of implementation, in improving mental health and quality of life in elderly people in a nursing home.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • both sexes, aged ≥ 65 years, with an optimal level of functional and cognitive abilities necessary to perform the exercises and understand the measurement scales.

Exclusion criteria

  • significant cognitive and neurological impairments, functionally immobile persons, and persons who refuse to participate.

Treatment and study plan

Physiotherapy

Behavioral
  • Exercise therapy - stretching and breathing exercises, stabilization exercises, mobility exercises, and balance and coordination exercises.

The exercises will be performed in a standing and lying position, with the possibility of using aids - gymnastic ball and resistance bands. Implementation - three times a week for 40 minutes, for a total of four weeks.

  • Walking activity - three times a week for half an hour.
  • Education on optimal positions and movement in everyday life activities - at the beginning of the study in one session lasting 60 minutes.

Primary outcomes

  1. Depression and Anxiety

    Time frame: From enrollment to the end of treatment at 4 weeks

    Hospital Anxiety and Depression Scale (0=best, 21=worst)

Secondary outcomes

  1. Self-reported measure of health

    Time frame: From enrollment to end of the treatment at 4 weeks

    The 36-Item Short Form Survey; Eight domains: Physical functioning, Role limitations due to physical health, Role limitations due to emotional problems, Energy/fatigue, Emotional well-being, Social functioning, Pain and General Health (0 - worst, 100 - best)

  2. Range of motion of extension and flexion in the lumbar spine

    Time frame: From enrollment to the end of treatment at 4 weeks

    Goniometer (extension 0-40°, flexion 0-70°; higher score best)

Sponsors and collaborators

Lead sponsor

University of Mostar

Other

Registry information

Official study title

Effectiveness of Short-term Supervised Group Exercise Therapy, Walking and Education on Mental Health, Quality of Life and Mobility in Elderly Residents of Nursing Homes

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Nov 19, 2025
Registry last updated
Jan 12, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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