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OpenTrials
Completed

NCT Number: NCT05206253

Effectiveness of Egg Versus Whey Protein Powder During Resistance Training

Consumption of whole eggs has recently been shown to stimulate muscle protein synthesis to a greater degree than consumption of egg whites after a resistance training session. It is theorized that the egg yoke contains bio-active nutrients that enhance the protein provided by egg whites. The study will evaluate the effect of whole egg powder compared to whey protein powder and placebo over 12 weeks of resistance training in men and women who are participating in resistance training programs.

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Key information

Conditions

Muscle Atrophy Atrophy Muscular Atrophy Nervous System Diseases Neurologic Manifestations Neuromuscular Manifestations Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Regina, Regina, Saskatchewan, Canada

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About this study

Consuming whole eggs after resistance training sessions appears to be more effective for simulating muscle protein synthesis that simply consuming egg whites. The egg yolks might enhance the effect of protein derived from egg whites. The study will compare post-exercise supplementation with about 30 grams of protein derived from whole egg powder versus whey protein powder and placebo (maltodextrin) over a 12-week resistance training program. Resistance-trained men and women (n=120) will be randomized to consume either the whole-egg powder, whey protein powder or maltodextrin after resistance training 6 times per week for 12 weeks. The primary outcome measure is change in lean tissue mass. Secondary measures include change in fat mass, change in arm and leg muscle thickness, change in bench press, squat, and knee extension strength, and change in fasting blood glucose.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Resistance training experience for at least one year

Exclusion criteria

  • Having taken any nutritional supplements the past 30 days
  • Currently using anabolic steroids
  • Currently taking corticosteroids
  • Allergies to dairy or egg products
  • Identifying any medical conditions as determined by the "Get Active Questionnaire"

Treatment and study plan

Whole egg powder

Dietary Supplement

Nutritional supplementation during a 12 week resistance training program

Whey protein powder

Dietary Supplement

Nutritional supplementation during a 12 week resistance training program

Maltodextrin placebo

Dietary Supplement

Nutritional supplementation during a 12 week resistance training program

Primary outcomes

  1. Change in lean tissue mass

    Time frame: 12 weeks

    Lean tissue mass measured by DXA

Secondary outcomes

  1. Change in fat mass

    Time frame: 12 weeks

    Fat mass measured by DXA

  2. Change in biceps muscle thickness

    Time frame: 12 weeks

    biceps muscle thickness measured by ultrasound

  3. Change in triceps muscle thickness

    Time frame: 12 weeks

    triceps muscle thickness measured by ultrasound

  4. Change in quadriceps muscle thickness

    Time frame: 12 weeks

    quadriceps muscle thickness measured by ultrasound

  5. Change in hamstrings muscle thickness

    Time frame: 12 weeks

    hamstrings muscle thickness measured by ultrasound

  6. Change in bench press strength

    Time frame: 12 weeks

    Bench press strength (kg)

  7. Change in leg squat strength

    Time frame: 12 weeks

    Leg squat strength (kg)

  8. Change in knee extension strength

    Time frame: 12 weeks

    Isokinetic knee extension torque

  9. Change in fasting glucose

    Time frame: 12 weeks

    Fasting glucose

Sponsors and collaborators

Lead sponsor

University of Saskatchewan

Other

Collaborators

  • Egg Farmers of Canada

Registry information

Official study title

Egg Versus Whey Protein as the Optimal Supplement for Fitness-conscious People

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Jan 25, 2022
Registry last updated
May 29, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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