Skip to main content
OpenTrials
Completed

NCT Number: NCT03345394

Effectiveness of Contingency Management in the Treatment of Crack Addiction in Brazil

Crack addiction has become a severe public health problem in Brazil. Crack users present elevated prevalence rates of psychiatric comorbidities, sexual transmitted infections and unemployment with high probability of living or have lived in the streets, history of incarceration and engagement in illegal activities. For the last 20 years a treatment called Contingency Management (CM) have achieved the best results regarding reduction of substance use, promotion of abstinence, treatment attendance and retention in treatment. The first CM study conducted in Brazil advocates for the efficacy of CM on all of these outcomes, suggesting that CM can be effective in a Brazilian population of crack users.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Substance Use Disorders Addiction, Cocaine Chemically-Induced Disorders Cocaine-Related Disorders Contingency Management Mental Disorders Substance-Related Disorders

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Unidade Recomeço Helvétia

São Paulo, 01215-010, Brazil

About this study

The objective of this study is to evaluate the effectiveness of Contingency Management (CM) for crack users living in the "Crackland" region. To achieve this goal, regular treatment staff from Unidade Recomeço Helvétia treatment service will be capacitated in CM to latter-on apply the CM intervention in their respective services. The design will be a single-blind randomized clinical trial composed of a sample of 100 subjects with current diagnose for crack/cocaine dependence. Participants allocated to the control condition will receive 12 weeks of the usual care treatment provided by these two treatment facilities. Participants allocated to the experimental condition will receive the exact same treatment as control participants associated with CM. CM procedure will occur 2 timer per week (every Monday and Thursday or Tuesday and Friday). Primary outcomes are: (1)retention in treatment; (2) reduction of crack use; (3) promotion of continuous crack cocaine abstinence. Secondary findings are reduction on psychiatric symptomatology. The investigator hypothesis is that participants in the CM condition will have a better treatment response in all studied outcomes.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • DSM-V diagnose for crack cocaine use disorder

Exclusion criteria

  • being under 18 years old

Treatment and study plan

Contingency Management

Behavioral

Participants will receive vouchers with monetary value for submitting crack cocaine negative urine samples

Standard treatment

Behavioral

Participants will receive the standard treatment offered at Unidade Recomeço Helvétia treatment program

Primary outcomes

  1. Pattern of Crack Cocaine Use

    Time frame: 12 weeks

    Percentage of negative crack cocaine urine samples submitted during the 12 weeks of treatment

  2. Promotion of Continuous Crack Cocaine Abstinence

    Time frame: 12 weeks

    Longest duration of continuous abstinence achieved (in weeks)

Secondary outcomes

  1. Treatment Retention

    Time frame: 12 weeks

    time elapsed between treatment entry and last time present in treatment (in weeks)

Sponsors and collaborators

Lead sponsor

Federal University of São Paulo

Other

Collaborators

  • Washington State University

Registry information

Official study title

Effectiveness of Contingency Management in the Treatment of Crack Addiction for Individuals Living in the "Crackland" Region. A Single-blind Randomized Controlled Trial

Important dates

Study start
2017
Primary completion
2020
Study completion
2020
First posted
Nov 17, 2017
Registry last updated
Apr 8, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.