Effectiveness of Combination Therapy of Microneedling and Minoxidil in Androgenetic Alopecia of Indonesian Men

The goal of this clinical trial is to compare the effectiveness of combination therapy of microneedling and minoxidil in androgenetic alopecia of Indonesian men. The main questions it aims to answer are:

* Is there an increase in hair density with combination therapy of microneedling and minoxidil versus minoxidil monotherapy? * Is there an increase in hair diameter with combination therapy of microneedling and minoxidil versus minoxidil monotherapy?

Participants will be divided into 2 groups. The first one will receive minoxidil monotherapy, and the second one will receive a combination therapy of microneedling and minoxidil. Researchers will compare those 2 groups to see if there is a difference of effectiveness based on hair density and diameter.

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Key information

Conditions

Androgenetic Alopecia Alopecia Hair Diseases Hypotrichosis Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Skin Diseases Skin and Connective Tissue Diseases

Age range

18 year–59 year

Sex eligibility

Male

Study type

Interventional

Phase

Phase 3

Primary location

Cipto Mangungkusumo Hospital

Jakarta, DKI Jakarta, 10430, Indonesia

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Male
Indonesian
Age 18-59 years
Diagnosis of androgenetic alopecia
Hamilton-Norwood type III-IV

Exclusion criteria

Use of minoxidil or finasteride topical 1 month prior
Use of minoxidil or finasteride oral 1 month prior
Skin infection in the treatment area
Cosmetic procedures for the treatment of alopecia androgenetic such as platelet rich plasma, laser therapy,or microneedling 3 months prior
History of keloid

Treatment and study plan

Minoxidil 5% Topical Solution

Drug

Patient will be given minoxidil 5% topical solution, twice a day for 12 weeks

microneedling

Device

Patient will be given microneedling treatment every 4 weeks

Primary outcomes

Density of hair

Time frame: 12 weeks

Increase density of hair in alopecia androgenetic patient
Diameter of hair

Time frame: 12 weeks

Increase diameter of hair in alopecia androgenetic patient

Sponsors and collaborators

Lead sponsor

Indonesia University

Other

Registry information

Important dates

Study start: 2023
Primary completion: 2023
Study completion: 2023
First posted: Aug 14, 2023
Registry last updated: Sep 28, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed