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Completed

NCT Number: NCT00060762

Effectiveness of Binge Eating Disorder Treatments

This study will evaluate the long-term effectiveness of interpersonal psychotherapy, behavioral weight loss interventions, and guided self help treatments in treating binge eating disorder (BED).

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Key information

Conditions

Eating Disorders Body Weight Body Weight Changes Feeding and Eating Disorders Mental Disorders Pathological Conditions, Signs and Symptoms Signs and Symptoms Signs and Symptoms, Digestive Weight Loss

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

W. Stewart Agras, Stanford, California, United States

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About this study

BED is a serious condition that is associated with psychiatric comorbidity, psychosocial impairment, and obesity. Interpersonal psychotherapy (IPT), behavioral weight loss (BWL) interventions, and guided self help (GSH) treatments for BED have been evaluated, but the safest and most effective treatment has not yet been identified. This study will determine which of these three treatments is most effective in treating BED.

Participants are stratified by negative affect subtype and are randomly assigned for 6 months to one of three treatment groups: IPT, BWL, or GSH. IPT focuses on current interpersonal problems which are hypothesized to increase negative affect and lead to binge eating. BWL interventions involve the adoption of weight loss inducing behaviors. GSH is a shortened version of cognitive behavioral therapy that focuses directly on eating behavior. IPT and BWL patients have 20 treatment sessions; those receiving GSH have 10 sessions. Assessments are made pre-treatment, post-treatment, and at 6, 12, 18, and 24 months after treatment is complete.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • DSM-IV criteria for Binge Eating Disorder
  • Body Mass Index (BMI) between 27 and 45

Exclusion criteria

  • Body Mass index > 45
  • Current psychosis
  • Current bipolar disorder
  • Alcohol or drug dependence within last 6-months

Treatment and study plan

Interpersonal Therapy

Behavioral

20 sessions of interpersonal therapy were provided over a 6-month period

Other names: IPT

Behavioral Weight Loss Treatment

Behavioral

20 sessions of behavioral weight loss treatment were provided over a 6-month period

Other names: BWL; Weight loss treatment

Guided Self Help

Behavioral

10 sessions of guided self help were provided over a 6-month period

Other names: GSH

Primary outcomes

  1. Binge eating

    Time frame: Pre-treatment, 6, 12, and 24-months

    Rate of binge eating

Secondary outcomes

  1. Eating disorder psychopathology

    Time frame: pre-treatment, 6, 12, 24 months

    Assessed by the Eating Disorder Examination

Sponsors and collaborators

Lead sponsor

Stanford University

Other

Collaborators

  • National Institute of Mental Health (NIMH)

Registry information

Official study title

Effectiveness of Psychological Treatments for BED

Important dates

Study start
2002
Primary completion
2007
Study completion
2007
First posted
May 13, 2003
Registry last updated
May 15, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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