Effectiveness of Aspirin in Compare With Heparin Plus Aspirin in Recurrent Pregnancy Loss Treatment

This study evaluated the effect of anticoagulant treatment on the live-birth rate in women with a history of at least two continuous unexplained miscarriages or thrombophilia. It also compared two methods of treatment with aspirin and aspirin plus heparin.

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Key information

Conditions

Recurrent Pregnancy Loss

Age range

19 year–35 year

Sex eligibility

Female

Study type

Observational

Primary location

Research and Clinical Centre for Infertility

Yazd, Yazd Province, Iran

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

unexplained recurrent miscarriage,
women had previous venous or arterial thromboembolism or who were heterozygous or homozygous for mutations for FV Leiden G1691A, prothrombin gene G20210A (FII G20210A), and methyltetrahydrofolate reductase C677T (MTHFR C677T)

Exclusion criteria

abnormal karyotypes of both partners,
uterine and cervical anatomical disorders on pelvic ultrasonography or hysteroscopy,
abnormal ovaries and abnormal endocrine tests.

Sponsors and collaborators

Lead sponsor

Yazd Medical University

Other

Registry information

Important dates

Study start: 2008
First posted: Mar 2, 2012
Registry last updated: Mar 2, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed