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Enrolling by Invitation

NCT Number: NCT07475611

Effectiveness of an Interactive Screen in the Rehabilitation of Neglect in Adults With Subacute Stroke: A Randomized Controlled Trial in Argentina.

Hemispatial neglect is one of the most frequent and disabling sequelae after a stroke, particularly following right-hemisphere lesions. Its prevalence ranges from 25% to 80% and is associated with poorer functional outcomes, increased risk of falls, prolonged hospital stays, and lower rates of discharge to home. In response to these challenges, rehabilitation technologies have emerged as promising tools, especially during the subacute phase of stroke, a critical period for neuroplasticity. The MYRO® device-an adjustable interactive screen that enables intensive, task-oriented training-has shown benefits in promoting visual scanning, midline crossing, and sensorimotor integration through personalized exercises with constant feedback.

This study aims to evaluate the effectiveness of MYRO® combined with conventional occupational therapy in patients with left hemispatial neglect secondary to subacute stroke. A randomized clinical trial will be conducted with 30 participants assigned to two groups: conventional occupational therapy (OT-C) and occupational therapy plus rehabilitation technology using MYRO® (OT-M). Both groups will receive interventions for four weeks, with assessments at baseline, at the end of the protocol, and at a six-week follow-up. Outcome measures will include the NIHSS, FIM, Catherine Bergego Scale, Cancelation Bells Test, and Line Bisection Test.

It is expected that the use of MYRO® will enhance visuospatial attention toward the left hemifield and accelerate functional recovery compared with conventional treatment alone. The results could provide relevant evidence supporting the integration of interactive technology into neurofunctional rehabilitation within the Argentine context.

Enrolling by Invitation

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Key information

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Right-sided stroke. Ischemic or hemorrhagic.
  • Currently in the subacute phase of recovery from the event (1 week to <6 months post-stroke).
  • Presence of left hemineglect as determined by the Catherine Bergego Scale and/or Cancel Bells Test and/or Line Bisection Test.
  • Age 18 to 88 years.
  • Native Spanish speaker.

Exclusion criteria

  • Bilateral stroke. Previous strokes.
  • Medically unstable condition.
  • Previous visual impairments that prevent interaction with the device screen.
  • Presence of severe left homonymous hemianopsia. Determined by the total absence of vision in the entire left visual field, evaluated by confrontation visual field testing during the neurological physical examination.
  • Severe aphasia that prevents the comprehension of simple instructions that guarantee the completion of the task, determined by an NIHSS scale with a score of 3 points on the aphasia subitem.
  • Severe attentional and executive function deficits that prevent the comprehension of simple instructions, determined by the Catherine Bergego Scale and/or Cancel Bells Test and/or Line Bisection Test.

Treatment and study plan

Myro Interactive Screen (Tyromotion) as a tool for occupational therapy approach in patients with unilateral neglect

Device

Use of the Myro Interactive Screen (Tyromotion) as a tool for occupational therapy approach in patients with unilateral neglect

occupational therapy conventional treatment

Other

Bottom - up, restorative occupational therapy approach to unilateral neglect

Primary outcomes

  1. Catherine Bergego Scale for Neglect

    Time frame: from the start of treatment until 4 weeks

    The Catherine Bergego Scale (CBS) is a functional assessment composed of 10 items, each scored on a 0-3 scale, resulting in a total score ranging from 0 to 30. A score of 0 indicates the absence of neglect, whereas a score of 30 reflects severe unilateral neglect. Higher total scores represent worse performance and greater severity of neglect, while lower scores indicate better functional outcomes. Severity levels are commonly categorized as follows: 1-10 points indicate mild behavioral neglect, 10-20 indicate moderate neglect, and 21-30 represent severe behavioral neglect.

Sponsors and collaborators

Lead sponsor

Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia

Other

Registry information

Important dates

Study start
2025
Primary completion
2026
Study completion
2027
First posted
Mar 16, 2026
Registry last updated
Mar 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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