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Completed

NCT Number: NCT00659087

Effectiveness of a Femoral Block Following Total Knee Arthroplasty (TKA)

Hospital stays after total joint replacement surgery have been getting shorter over the past 10 years. This is mostly due to new ways to manage pain and early rehabilitation. To be able to go home safely soon after surgery, patients need to:

* 1) have adequate pain control * 2) be able to move through activities of daily living on their own (using aids)

Femoral nerve block, in combination with pain medications, is one of the new treatment strategies that are currently being used at other hospitals in Canada, the United States and the United Kingdom. Nerve blocks involve a needle filled with local anesthetic into the nerve that allows the feeling of pain around the knee. With good pain management, patients will be able to more quickly bend their knee and regain the ability to walk with aids and move from sitting and lying positions to standing and walking. Once they can do these activities with adequate pain control, they can be discharged from hospital to continue recovery at home. The purpose of this study is to examine a new way of managing postoperative pain and encourage early knee flexion and mobility, while maintaining pain control for patients after total knee replacement. We believe that patients who receive the nerve block in addition to the regular pain medication will have more knee flexion at discharge and experience less pain than patients who only receive usual pain medications.

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Key information

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

University of Alberta Hospitals

Edmonton, Alberta, T6G 2B7, Canada

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Undergoing primary total knee arthroplasty
  • English-speaking
  • Preoperative knee ROM > 90 degrees
  • Body Mass Index < 40

Exclusion criteria

  • Regular preoperative opioid use
  • Hepatic insufficiency
  • Any contra-indications to receiving a femoral block

Treatment and study plan

femoral block

Procedure

Those receiving femoral block postoperatively

Usual Care

Other

Those receiving only usual pain management postoperatively

Primary outcomes

  1. knee flexion

    Time frame: at hospital discharge or day 4 postoperatively, whichever is earlier

Secondary outcomes

  1. pain

    Time frame: daily in hospital, 2 weeks, 6 weeks, 12 weeks

  2. length of hospital stay

    Time frame: during hospitalization

  3. nausea/vomiting

    Time frame: during hospitalization

  4. participation in rehabilitation

    Time frame: day of surgery

Sponsors and collaborators

Lead sponsor

Edmonton Civic Employees Research Fund

Other

Registry information

Official study title

A Pilot Study of the Feasibility of Early Discharge After Total Knee Arthroplasty Using a Femoral Nerve Block

Important dates

Study start
2008
Primary completion
2009
Study completion
2009
First posted
Apr 16, 2008
Registry last updated
Aug 3, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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