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Enrolling by Invitation

NCT Number: NCT06039488

Effectiveness of a Cancer Exercise Program

The investigators are examining the impact of an 8-week multi-modal exercise program (resistance and cardiovascular training) delivered 2 times per week on physical function adults (>18 years old) with cancer.

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Key information

Conditions

Cancer Behavior Motor Activity Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of South Carolina

Columbia, South Carolina, 29205, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults > 18 diagnosed with cancer

Exclusion criteria

  • unwilling to come to the on-site clinic for exercise sessions
  • any neuromuscular, cardiovascular, or psychological condition precluding safe exercise
  • unable to read/understand English.

Treatment and study plan

Exercise

Behavioral

A combination of resistance exercise and cardiovascular exercise (performed 2 days per week for 8-weeks) is tailored to each individual in accordance with their medical/cancer-related history, baseline assessments of physical function, and overall goals.

Resistance exercise includes 6-8 exercises targeting major muscle groups. The first week of the program is used to familiarize participants to the exercises of the program, provide coaching on safe and appropriate technique, and identifying initial load for 2 sets of 12 repetitions (equivalent to ~65% 1 repetition maximum), with a goal of working towards 4 sets of 8 reps. Additionally, participants are asked to perform 20-30 minutes of moderate-to-vigorous aerobic activity (approximately 60-85% age-predicted heart rate maximum) via walking, jogging, or cycling each session.

Primary outcomes

  1. Bellarmine Norton Assessment Tool (2-minute Step Test)

    Time frame: 0 and 8-weeks

    2-minute Step Test: Number of times an individuals' knee reaches a predetermined heigh during a 2-minute period of marching

  2. Bellarmine Norton Assessment Tool (Timed Arm Curl)

    Time frame: 0 and 8-weeks

    Timed Arm Curl: Number of repetitions an arm curl individuals can complete in 30 seconds)

  3. Bellarmine Norton Assessment Tool (30 second Chair Stand)

    Time frame: 0 and 8-weeks

    Chair Stand: Number of times participants can stand from a sitting position and return to sitting in 30 seconds

Secondary outcomes

  1. Fatigue

    Time frame: 0 and 8-weeks

    The Functional Assessment of Chronic Illness Therapy (FACIT) Fatigue Scale: The FACIT-Fatigue scale is a 13-item scale that will be used to assess cancer-related fatigue. The FACIT-Fatigue scale is scored on a 0-4 response scale from 0 = "not at all" to 4 "very much", regarding items related to fatigue and energy in the past 7 days. Lower score indicates greater fatigue

Sponsors and collaborators

Lead sponsor

University of South Carolina

Other

Registry information

Official study title

The Impact of an 8-week Exercise Program on Physical Function in Individuals With Cancer

Important dates

Study start
2021
Primary completion
2026
Study completion
2027
First posted
Sep 15, 2023
Registry last updated
Sep 15, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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