Skip to main content
OpenTrials
Completed

NCT Number: NCT01659125

Effectiveness and Neuropsychological Predictors of Guided Self-Help for Obsessive-Compulsive Disorder (OCD)

The primary aim of this study is to learn about who is most likely to benefit from guided self-help (GSH) for obsessive-compulsive disorder (OCD).

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Obsessive-Compulsive Disorder Anxiety Disorders Mental Disorders

Age range

18 year–69 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hartford Hospital

Hartford, Connecticut, 06106, United States

About this study

40 Participants with OCD will be recruited. They will be given access to OC Fighter, an internet OCD treatment program. During the 17 week program, participants will meet with a therapist 9 times. Assessments will occur at pretreatment, post-treatment, 3-month follow up and 6-month follow up.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Principal or co-principal diagnosis of OCD
  • Clinical global impression score greater than or equal to 4
  • Y-BOCS score great than or equal to 8
  • Fluency in English
  • Capacity to understand the nature of the study and willingness to sign informed consent form

Exclusion criteria

  • Active manic episode, psychosis, pervasive developmental disorder, mental retardation
  • Concurrent OCD psychotherapy
  • Current threat of harm to self or others
  • Previous adequate trial of therapist-administered or self-administered exposure and response prevention for OCD

Treatment and study plan

"OCFighter"

Behavioral

OCFighter™ s an interactive, internet guided self-help (GSH) treatment program for obsessive-compulsive disorder (OCD). It uses the evidence based approach known as Cognitive Behavioral Therapy (CBT) and was adapted from the previously validated BT STEPS program for OCD. The program teaches the best practice CBT technique to help with OCD called exposure with ritual prevention (ERP).

Other names: OCFighter, Guided Self-help

Primary outcomes

  1. Change in Yale-Brown Obsessive-Compulsive Scale (Y-BOCS)

    Time frame: Baseline (pretreatment), 17-weeks (posttreatment), and 6 month-follow-up

    The Y-BOCS is a semi-structured interview that assesses severity of obsessions and compulsions. The total score is reported here and ranges from 0 to 40 with higher scores indicating more severe OCD symptoms.

  2. Responder Status

    Time frame: Week 17 (post-treatment) and 6-month follow-up

    Participants who experienced a clinically significant change in Y-BOCS score defined as posttreatment YBOCS score that (a) has decreased by a reliable level (at least 1.96 times the standard deviation of that measure, taking into account the reliability of the measure itself; in this case, a decrease of 5 points or more), and (b) is within the nonclinical range of scores (in this case, a score of 13 or below).

Sponsors and collaborators

Lead sponsor

Hartford Hospital

Other

Registry information

Official study title

Effectiveness and Neuropsychological Predictors of Guided Self-Help for OCD

Important dates

Study start
2012
Primary completion
2014
Study completion
2014
First posted
Aug 7, 2012
Registry last updated
Jan 7, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.