Skip to main content
OpenTrials
Completed

NCT Number: NCT05961020

Effect of Whole-body Vibration on Insulin Resistance in Obese Postmenopausal Women.

This study will be conducted to investigate the Effect of whole-body vibration on insulin resistance in obese postmenopausal women

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Insulin Resistance Glucose Metabolism Disorders Hyperinsulinism Metabolic Diseases Nutritional and Metabolic Diseases

Age range

50 year–60 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Kerolous Ishak Shehata kelini

Cairo, Egypt

About this study

The prevalence of obesity has tripled over the past four decades, imposing an enormous burden on people's health.

Obesity is associated with premature mortality and is a serious public health threat that accounts for a large proportion of the worldwide non-communicable disease burden, including type 2 diabetes, cardiovascular disease, hypertension, and certain cancers.

reported that "Whole-body vibration (WBV) training has been established as a useful method to improve physical fitness in obese individuals. Vibration stimulus during half squatting might suggest a long-term effect of WBV on the endocrine system. Therefore, in this study, The aim to investigate the effect of whole-body vibration on insulin resistance in obese postmenopausal.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All women were postmenopausal with no menses at least 1 year.
  • Their ages were ranged from 50-60 years old.
  • Their body mass index (BMI) > 30 kg/m2.
  • They were not engaged in any other treatment program.

Exclusion criteria

  • Women with body mass index (BMI) < 30 kg/m2.
  • Any cardio-respiratory diseases.
  • Diabetes mellitus.
  • with malignancy.
  • with severe hemorrhage, acute viral disease and mental disorders.
  • Smokers.
  • Women with life threatening disorders as renal failure

Treatment and study plan

Total body vibration

Device

Whole-body vibration (WBV) training has been established as a useful method to improve physical fitness in obese individuals. Vibration stimulus during half squatting might suggest a long-term effect of WBV on the endocrine system

moderate restricted diet

Other

moderate restricted diet

Primary outcomes

  1. The Homeostatic model assessment (The HOMA-IR).

    Time frame: up to 3 months

    The Homeostatic model assessment (The HOMA-IR).

    A sample of 5ml of venous blood sample was drawn from all women after 12 hours fasting for measurement of fasting blood glucose, fasting blood insulin and then detection of insulin resistance (by HOMA -IR) through the equation:

    HOMA-IR=(Glucose ×Insulin)/405 glucose in mass unit (mg/dl)

  2. BMI

    Time frame: up to 3 months

    Weight and height were measured to detect the BMI according to the following equation: BMI= weight/height² (Kg/m²)

  3. Waist circumference

    Time frame: up to 3 months

    A non-stretchable tape measurement was used to measure waist circumference for all women in both groups A and B: mid-way between upper border of the lateral iliac crest and the lower border of the lowest rib at the end of gentle expiration with arm relaxed at sides.

  4. Skin fold thickness

    Time frame: up to 3 months

    Skin fold caliper was used to measure skin fold thickness at abdominal region for all women in both groups A and B

Sponsors and collaborators

Lead sponsor

October 6 University

Other

Registry information

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Jul 27, 2023
Registry last updated
May 17, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.