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OpenTrials
Completed

NCT Number: NCT00416156

Effect of Weight Reduction on Inflammatory Markers and Genes Expression in Obese Individuals

To investigate whether weight reduction by life style modification for 12 weeks will improve circulating inflammatory markers, adipocytokines as well as gene expression of proinflammatory protein obtained from circulating monocytes from obese individuals.

Completed

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Key information

Conditions

Obesity Body Weight Inflammation Nutrition Disorders Nutritional and Metabolic Diseases Overnutrition Overweight Pathologic Processes Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

20 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Taichung Veterans General Hospital

Taichung, Taiwan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Nondiabetes obese individuals with BMI greater than 27 kgs/m2

Exclusion criteria

  • Diabetes
  • Abnormal hepatic, renal and cardiac function

Treatment and study plan

Lifestyle Modification

Behavioral

Primary outcomes

  1. Inflammatory responses after weight reduction

Secondary outcomes

  1. BMI

  2. Circulating inflammatory markers

  3. Adipocytokines

  4. Gene Expression from mononuclear cells

Sponsors and collaborators

Lead sponsor

Taichung Veterans General Hospital

Other

Registry information

Important dates

Study start
2005
Study completion
2005
First posted
Dec 27, 2006
Registry last updated
Dec 27, 2006

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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