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OpenTrials
Completed

NCT Number: NCT00813553

Effect of β-alanine Supplementation on Muscle Carnosine

Carnosine is a natural acid buffering substance of muscle. The primary objective of this study is to test whether a nutritional supplement of beta-alanine enhances carnosine content in muscle.

Completed

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Key information

Conditions

Healthy Behavior Motor Activity

Age range

18 year–40 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

University and Inselspital

Bern, Canton of Bern, 3010, Switzerland

About this study

Volunteers will be randomized to receiving 3 nutritional supplements. Two supplements contain beta-alanine at different doses, the third supplement is a placebo.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Stable health as evaluated by medical evaluation
  • Body mass index higher than 18 kg/m2
  • Body mass index lower than 25 kg/m2, unless body fat is less than 20%

Exclusion criteria

  • intolerance to β-alanine,
  • allergy to soy, fish and crustacean
  • participation in another intervention study
  • consumer of dietary supplement susceptible to contain beta-alanine
  • determined to have very high baseline muscle carnosine concentration

Treatment and study plan

Placebo

Dietary Supplement

daily

Beta-alanine

Dietary Supplement

daily

Primary outcomes

  1. muscle carnosine concentration

    Time frame: 0 to 8 weeks

Sponsors and collaborators

Lead sponsor

Société des Produits Nestlé (SPN)

Industry

Collaborators

  • Insel Gruppe AG, University Hospital Bern
  • University of Bern

Registry information

Official study title

Effect of Two 8-week β-alanine Supplementation Protocols on Muscle Carnosine

Acronym: LitmusMagnet

Important dates

Study start
2008
Primary completion
2009
Study completion
2009
First posted
Dec 23, 2008
Registry last updated
Apr 25, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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