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OpenTrials
Completed

NCT Number: NCT00706277

Effect of Total Intravenous Anesthesia and Balanced Anesthesia on Postoperative Lung Function

The aim of the study is to investigate the effects of total intravenous anesthesia (TIVA; propofol, remifentanil) and balanced anesthesia (BAL; induction with propofol and fentanyl; maintenance of anesthesia with sevoflurane and nitrous oxide) on pulmonary function 30 minutes after emergence from the general anesthesia.

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Key information

Conditions

Lung Function

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

TILAK Hospitals

Innsbruck, 6020, Austria

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ASA 1-2
  • BMI normal

Exclusion criteria

  • lung disease
  • Nicotine abuse

Treatment and study plan

Propofol

Drug

propofol 2mg/kg for induction of anesthesia; followed by propofol 6 mg/kg/hour

Remifentanil

Drug

remifentanil 0,25mcg/kg/hour

Fentanyl

Drug

fentanyl 100mcg

sevoflurane/nitrous oxide

Drug

maintenance of anesthesia with sevoflurane and nitrous oxide

Primary outcomes

  1. FEV1 forced expiratory volume; FVC forced vital capacity

    Time frame: preoperative, 30 minutes postoperative

Sponsors and collaborators

Lead sponsor

Medical University Innsbruck

Other

Registry information

Important dates

Study start
2008
Study completion
2008
First posted
Jun 27, 2008
Registry last updated
Feb 10, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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