Effect of Topical Dexmedetomidine on Intraocular Pressure

Evaluate the short-term safety and efficacy of dexmedetomidine (0.0055%) drops on intraocular pressure (IOP) in healthy eyes.

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Key information

Conditions

Glaucoma Eye Diseases Intraocular Pressure Ocular Hypertension

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Beirut Eye Specialist Hospital

Beirut, 116-5311, Lebanon

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients with healthy eyes and no history of glaucoma

Exclusion criteria

history of glaucoma, IOP > 24mmHg at baseline, abnormal optic nerve on fundus examination, keratoconus, corneal graft, corneal edema or a history of refractive surgery

Treatment and study plan

Dexmedetomidine

Drug

Instillation of eyedrops

balanced salt solution

Drug

instillation of eyedrop

Primary outcomes

Intraocular pressure change

Time frame: at presentation, 30 minutes, 4 hours and 24 hours after instillation

Taken by aplanation tonometry

Sponsors and collaborators

Lead sponsor

Beirut Eye Specialist Hospital

Other

Registry information

Official study title

The Effect of Topical Dexmedetomidine (0.0055%) on Intraocular Pressure in Healthy Eyes: a Randomized Controlled Trial

Important dates

Study start: 2017
Primary completion: 2018
Study completion: 2018
First posted: Oct 1, 2018
Registry last updated: Oct 3, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed