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OpenTrials
Completed

NCT Number: NCT07357883

Effect of Topical Argan Oil on Healing After Laser Depigmentation.

Effect of Argan oil vs placebo on healing after laser depigmentation

Completed

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Key information

Conditions

Gingival Hyperpigmentation Laser Depigmentation Postoperative Gingival Healing Topical Argan Oil

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Dentistry, Cairo University

Cairo, Cairo Governorate, Egypt

About this study

Evaluate the effect of Argan oil vs. placebo on post-operative healing after laser depigmentation. as well as Compare pain levels (VAS score), gingival pigmentation recurrence, and patient satisfaction between groups at predetermined follow-up intervals.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged 18-40 with moderate/severe physiological gingival pigmentation
  • Good general and periodontal health.

Exclusion criteria

  • Systemic diseases affecting healing (e.g., uncontrolled diabetes).
  • Smokers or tobacco chewers.
  • Pregnant/lactating women.
  • Previous depigmentation procedures in the last 2 years.

Treatment and study plan

Laser Depigmentation

Procedure

Laser protocol:

Diode laser, wavelength 810-980 nm, continuous mode, initiated fiber tip 400 µm, power 1.5-2 W.

Primary outcomes

  1. Effect of Argan oil

    Time frame: 14 days

    Evaluate the effect of Argan oil vs. placebo on post-operative Gingival healing

Secondary outcomes

  1. Visual Analog Scale (VAS)

    Time frame: 14 days

    Compare pain levels (VAS score) , gingival pigmentation recurrence, and patient satisfaction between groups.

Sponsors and collaborators

Lead sponsor

Ghada Adayil

Other

Registry information

Official study title

Comparative Evaluation of Argan Oil as a Post-Operative Agent Versus Placebo Following Laser Gingival Depigmentation: A Randomized Controlled Clinical Trial

Important dates

Study start
2025
Primary completion
2025
Study completion
2026
First posted
Jan 22, 2026
Registry last updated
Jan 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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