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Completed

NCT Number: NCT07280182

Effect of the Quadratus Lumborum Block Versus the Lumbar Plexus for Spiral Thighplasty Surgery

Whether trans muscular QLB provides postoperative analgesia compared with LPB after thigh lift surgery

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Key information

Conditions

Analgesia Agnosia Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Perceptual Disorders Signs and Symptoms

Age range

18 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of medicine,Menofia university hospitals

Cairo, Shibin El Kom, 32511, Egypt

About this study

Adequate analgesia after spiral thigh reduction (thigh lift) is essential for early mobilization and patient satisfaction. Quadratus lumborum block (QLB) has shown analgesic efficacy comparable to lumbar plexus block (LPB) for hip area surgery with potential advantages in motor-sparing and safety

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ASA ( American Society of Anaesthesia) I-II
  • elective bilateral spiral thigh lift under general anesthesia
  • consent to regional block and trial participation

Exclusion criteria

  • Coagulopathy or therapeutic anticoagulation not meeting ASRA safety windows
  • infection at injection sites
  • allergy to local anesthetics
  • preexisting significant neuropathy
  • BMI > 35 kg/m² if impeding ultrasound visualization; renal/hepatic failure; pregnancy; inability to use NRS; chronic opioid use >60 mg oral morphine equivalents/day; contraindication to study analgesics.

Treatment and study plan

Ultrasound-Guided Trans-muscular QLB

Other

With the patient lateral decubitus position, a low-frequency curvilinear probe in the 'Shamrock' view at L2-L4. In-plane posterior-to-anterior needle advancement through the Quadratus lumborum to the interfascial plane anterior to QL and posterior to Psoas major. Inject 30 mL Bupivacaine 0.25% after negative aspiration and hydrodissection to confirm proper spread . Then the patient will be turned to the other side, and the block will be done with the same technique

Ultrasound-Guided Posterior Lumbar Plexus (Psoas Compartment) Block

Other

Lateral decubitus, Shamrock view to identify the Psoas compartment; in-plane needle advancement to the Psoas compartment adjacent to the transverse process. Inject 30 mL of Bupivacaine 0.25% in 5 mL increments, aspirating frequently. This will be done in the same position for both sides

Primary outcomes

  1. Visual analogue scale score

    Time frame: 24 hours

    Visual analogue scale score at 1st,6th,12th and 24 h (where 0 is interpreted as no pain, 1-4 mild pain, 5-6 moderate pain, 7-10 severe pain)

Secondary outcomes

  1. Time for first analgesic request

    Time frame: 24 hours

    first analgesic request

  2. Opioid consumption

    Time frame: 24 hours

    cumulative opioid consumption

  3. Time to walk >30 (meter)

    Time frame: 24 hours

    walk >30 (meter)

  4. Performance Time

    Time frame: minutes

    block performance time

  5. The number of patients who develop block-related complications

    Time frame: 24 hours

    nausea and vomiting , hypotension

  6. the patients Satisfaction questionnaire

    Time frame: 24 hours

    pateints are either : Dissatisfied Neither satisfied nor dissatisfied Satisfied Very satisfied

Sponsors and collaborators

Lead sponsor

Menoufia University

Other

Registry information

Official study title

Comparing the Early Postoperative Analgesic Effect of the Transmuscular Quadratus Lumborum Block Versus the Lumbar Plexus Block for Patients Undergoing Spiral Thighplasty Surgery

Acronym: QLB&LPB

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Dec 12, 2025
Registry last updated
Mar 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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