SC Neurochirurgia, Fondazione IRCCS Policlinico San Matteo
Pavia, 27100, Italy
NCT Number: NCT06620952
Posterior fossa surgery represents on of the most demanding procedure in neurosurgery. Retrosygmoid (RS), key-hole retrosygmoid (KR) and cerebellar hemispheric (CH) are the most common approaches used to access in this area. Despite they are not technically difficult to perform, these approaches can be burdened by postoperative cerebrospinal fluid (CSF) leakage, both at short and long-term follow-up, with an high risk of meningitis. Many techniques were employed to avoid this risk, but it can still be estimated between 2% and 11% according to literature1-4. Spena et al. reported a CSF leakage rate of 6.8% in a previous experience5. As a consequence, newer efforts are necessaries to avoid this potentially lethal complication. By this explorative study, we want to retrospectively analyzed our experience with a newer technique of bone closure, called O'Ring, in patients subdued to posterior fossa surgery by RS, KR and CH approaches, focusing on postoperative CSF leakage (primary objective), wound complications and subcutaneous CSF collections (secondary objectives).
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Notify Me18 year and older
All sexes
Observational
Pavia, 27100, Italy
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
"O-ring technique." consists on a different arrangement of fibrin-glue on a polymethilmetacrylate cranioplasty, with the aim to create a gasket to prevent CSF leakage
Time frame: 7 days
cumulative incidence of postoperative CSF leakage
Time frame: 1 and 3 months
cumulative incidence of CSF leakage at 1- and 3-months follow-up
Time frame: 1 and 3 months
cumulative incidence of wound complications postoperatively and at 1- and 3-months follow-up
Time frame: 1 and 3 months
cumulative incidence of subcutaneous CSF collections postoperatively and at 1 and 3-months radiological follow-up
Fondazione IRCCS Policlinico San Matteo di Pavia
Other
Acronym: O'Ring
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