Effect of the Duration of Preoperative Fasting on Hypotension Induced by General Anesthesia in the Elderly Person

This study aims to determine if prolonged fasting represents an independent risk factor for hypotension during induction of general anesthesia in the elderly.

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Key information

Conditions

Preoperative Fasting and Hypotension Cardiovascular Diseases Hypotension Vascular Diseases

Age range

70 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHRU de Brest

Brest, 29609, France

About this study

Preoperative fasting aims to reduce the risk of adverse events (eg, inhalation), but may be responsible for dehydration whose consequence is a major hypotension. This problem of hypotension is important because it (MAP <55 mmHg) is directly correlated to the occurrence of pejorative events on the cardiac and renal level and even more so that the duration of the hypotension is long.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Risk Score anesthetic ASA I-III
Patients ≥ 70 years
Suffering from a femoral neck fracture to be treated surgically:

either through prosthesis,
either by intramedullary nailing (gamma nail)

Exclusion criteria

Risk Score anesthetic ASA IV
Patient on Angiotensin Converting Enzyme (ACE) inhibitors or ARBs (ARA2) within 10 hours before surgery
Obesity (BMI> 35) or weight <40kg
Need to make a rapid sequence induction
Inability to achieve the femoral block (standardization of induction) or patient refusal with respect to the technique.

Treatment and study plan

Primary outcomes

Follow-up of the variation of the Mean arterial pressure

Time frame: 8 months

Sponsors and collaborators

Lead sponsor

University Hospital, Brest

Other

Registry information

Official study title

The Influence of Duration of Fluid Abstinence on Hypotension During General Anaesthesia Induction for Traumatic Hip Surgery in the Elderly

Acronym: JEÛNE PREOP

Important dates

Study start: 2014
Primary completion: 2015
Study completion: 2015
First posted: Sep 7, 2016
Registry last updated: Sep 7, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed