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Completed

NCT Number: NCT06086691

Effect of Strength Versus Endurance Training on Muscle Damage in Gym Athletes on Caffeine Supplementation.

Dietary supplements to enhance exercise and athletic performance come in a variety of forms, including tablets, capsules, liquids, powders, and bars. Many of these products contain numerous ingredients in varied combinations and amounts. Among the more common ingredients are amino acids, protein, creatine, and caffeine

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Key information

Conditions

Muscle Damage

Age range

18 year–40 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Riphah International University (RIU)

Islamabad, 44000, Pakistan

About this study

Caffeine is a popular nutritional supplement among gym athletes. It is frequently used as an ergogenic aid to improve physical performance, delay fatigue, and increase muscle power. This research aims to evaluate the effectiveness of caffeine through the blood sample test (Serum CK, LDH levels, AST levels) on muscle damage of gym athletes who are performing aerobic and strength training. This study would help understand the effects of strength training and endurance training on muscle damage in gym athletes who are consuming caffeine and to check the serum enzymes level of both groups who are on strength training and those who are on endurance level training, therefore, this study would help determine which athletes should be careful while consuming caffeine for a particular exercise regimen

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male gym athletes
  • Age: 18-40 years
  • Athletes with at least three days training session per week

Exclusion criteria

  • Athletes already on caffeine supplementation
  • Athletes with above normal serum enzyme levels

Treatment and study plan

Strength Training with Caffeine

Other

The intervention protocol consists of 5 types of strength training exercises. The following exercises will be performed for the strength training group:

  • bench press (3 sets of 10 reps)
  • biceps curl (3 sets of 10 reps)
  • triceps pushdown (3 sets of 10 reps)
  • leg press (3 sets of 10 reps)
  • leg extension (3 sets of 10 reps)

Strength training would be performed in 3 sets of 10 repetitions with 2 minutes of rest between each exercise. This protocol will be performed in a 30-40-minute session. 10-15 minutes of light warm-up activities will be performed before the start of each exercise session. The intervention sessions would be carried out with a 3-5-day gap between the two intervention sessions.

Endurance Training with Caffeine

Other

The intervention protocol consists of 3 types of endurance training exercises. The following exercises will be performed by this group:

  • Cycling (15 min)
  • Running (20 min)
  • Rowing (10 min)

The intervention sessions would be carried out with a 3-5-day gap between the two intervention sessions.

Primary outcomes

  1. Serum CK Levels

    Time frame: Pre-intervention, after 24 hours of the intervention, after 3 days before second intervention, and after 24 hours of the second intervention

    Serum CK level is the amount of an enzyme called creatine kinase (CK) in the blood. CK is a type of protein present in the muscle cells in human body need which is essential for proper functioning. Levels of CK can rise after a heart attack, skeletal muscle injury, or strenuous exercise

  2. Serum LDH levels

    Time frame: Pre-intervention, after 24 hours of the intervention, after 3 days before second intervention, and after 24 hours of the second intervention

    Lactate Dehydrogenase (LDH) is enzyme found in almost every cell of the human body, including your blood, muscles, brain, kidneys, and pancreas.

  3. Serum AST levels

    Time frame: Pre-intervention, after 24 hours of the intervention, after 3 days before second intervention, and after 24 hours of the second intervention

    Aspartate aminotransferase (AST) are enzymes found mainly in the liver, but also found in red blood cells, heart cells, muscle tissue and other organs, such as the pancreas and kidneys.

Secondary outcomes

  1. Rating of fatigue scale/Numeric Rating Scale-Fatigue

    Time frame: Pre-intervention, after 24 hours of the intervention, after 3 days before second intervention, and after 24 hours of the second intervention

    This rating-of-fatigue (ROF) scale has been developed which can track the intensity of perceived fatigue in a variety of contexts.

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Important dates

Study start
2022
Primary completion
2022
Study completion
2023
First posted
Oct 17, 2023
Registry last updated
Nov 13, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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