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Completed

NCT Number: NCT04228874

Effect of Stent Size on Dyssynchrony

the effect of stent size and number on left ventricular mechanical dyssynchrony after PCI using drug eluting stent is not clear enough

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Key information

Conditions

Left Ventricular Function

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

shaimaa Mostafa

Cairo, Egypt

About this study

Background: the effect of stent size and number on left ventricular mechanical dyssynchrony after PCI using drug eluting stent is not clear enough Aim: to study short term effect of stent size and number on left ventricular mechanical dyssynchrony after elective PCI to LAD artery.

Patients and methods: the study included 150 adult patients with electively stented LAD lesion with DES. Patients were evaluated pre PCI then follow up at 1m and 3m using tissue synchronization image (TSI).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • adult patients with electively stented LAD lesion with DES were enrolled in the study. Patients were evaluated pre PCI then follow up at 1m and 3m after PCI using TSI.

Exclusion criteria

  • patients with Bundle branch block (BBB),
  • Previous percutaneous coronary intervention (PCI),
  • Previous coronary artery bypass graft (CABG),
  • Rhythm other than sinus,
  • Rheumatic heart disease,
  • Prosthetic valve,
  • Complicated or unsuccessful procedure,
  • Patients with significant degenerative changes,
  • Patients with previous STEMI,
  • and dropped patients from follow up were excluded from the study.

Treatment and study plan

coronary artery stents

Device

Coronary angiography was done for all the patients according to the Judkins technique. All images were evaluated by an experienced operator, significant coronary artery disease was defined as > 70 % luminar diameter stenos. The following data was obtained:

  • Site of stent implantation within LAD. The first Diagonal branch serves as the boundary between the proximal and mid portion of the LAD. Thus, the portion of the artery prior to the origin of the 1st diagonal is known as the proximal LAD, while the segment just below the1st diagonal branch is the mid LAD. The distal segment of the LAD is the terminal third of the artery (Cao et al., 2017).
  • Length, diameter and number of stents.
  • TIMI flow after stent deployment.

Primary outcomes

  1. left ventricular systolic function

    Time frame: 3 months

Sponsors and collaborators

Lead sponsor

Benha University

Other

Registry information

Official study title

The Short Term Effect of Stent Size and Number on Left Ventricular Mechanical Dyssynchrony After Elective PCI to Left Anterior Descending Artery

Important dates

Study start
2018
Primary completion
2019
Study completion
2019
First posted
Jan 14, 2020
Registry last updated
Jan 14, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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