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OpenTrials
Completed

NCT Number: NCT07062419

Effect of Sonic Activation of Irrigant on Post Operative Pain After Root Canal Treatment

Fifty-eight patients aged 18-60 years, diagnosed with symptomatic or asymptomatic apical periodontitis will be randomly allocated into two groups: Group A (EndoActivator) and Group B (conventional syringe irrigation). preoperative pain will be evaluated in all patients requiring root canal treatment using visual analogue scale before initiating the procedure.

Postoperative pain will be measured using the Visual Analog Scale (VAS) at 24, 36, 48 hours and one week.

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Key information

Conditions

Post Operative Pain Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Root Canal Therapy Signs and Symptoms

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

28 Military Dental Centre

Lahore, Punjab Province, Pakistan

About this study

This randomized clinical study will evaluate the effect of two different irrigation techniques on postoperative pain following root canal treatment in patients with apical periodontitis. A total of 58 patients will be randomly assigned to one of two groups: one group will receive irrigation using the EndoActivator system, while the other group undergo conventional syringe irrigation. The objective is to determine whether the irrigation technique influences the level of postoperative discomfort experienced by patients. Pain levels will be assessed at specific time intervals to track the pattern of recovery and provide insight into the clinical effectiveness of each method in terms of patient comfort.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • irreversible pulpitis
  • symptomatic apical periodontitis
  • asymptomatic apical periodontitis
  • compliant patients
  • sufficient ferrule for post operative restoration

Exclusion criteria

  • periapical abcess
  • severe periodontal disease with guarded periodontal prognosis
  • teeth with guarded post operative restoration prognosis
  • non compliant patients

Treatment and study plan

endoactivator

Device

activation of irrigant during root canal treatment

Primary outcomes

  1. post operative pain using endoactivator

    Time frame: before procedure, after 24 hours, 36 hours , 48 hours, 1 week

    post operative pain will be marked on visual analogue scale (VAS). the lower the score the less pain will be and vice versa.

    maximum score 10 minimum score 0 0 to 10 depicting no pain to worst pain

  2. post operative pain

    Time frame: before procedure, after 24 hours , 36 hours , 48 hours , 1 week

    pain will be evaluatedon visual analogue scale (VAS). the lower the score the less pain will be and vice versa.

    maximum score 10 minimum score 0 0 to 10 depicting no pain to worst pain

Sponsors and collaborators

Lead sponsor

CMH Lahore Medical College and Institute of Dentistry

Other

Registry information

Official study title

The Effects of Sonic Activation of Irrigant on Post Operative Pain After Root Canal Treatment on Permanent Dentition: A Randomized Clinical Study

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jul 14, 2025
Registry last updated
Oct 1, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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