Effect of Sodium Chloride 5% Solution as an Adjuvant Treatment With Antimicrobial Therapy in the Treatment of Bacterial Infectious Keratitis

Prospective randomized control study to detect the effect of sodium chloride 5% solution as an adjuvant treatment with antimicrobial therapy in treatment of bacterial infectious keratits and to assess whether NaCl 5% accelerates epithelial healing, improves microbial eradication, and enhances visual outcomes in bacterial infectious keratitis.Data study will include two groups classified as follow : the first group will include treatment of microbial keratitis by antibiotic with sodium chloride 5% , the second group will include treatment by antibiotic only

IncluInclusion Criteria

• Age ≥ 18 years.
• Clinically diagnosed bacterial infectious keratitis
• Positive corneal scraping or strong clinical suspicion of bacterial cause.
• Ability to provide informed consent and attend follow-up visits

Exclusion criteria

• • Fungal, viral, or acanthamoeba keratitis.

• Recent (<7 days) topical corticosteroid use.
• Corneal perforation or impending perforation.
• History of hypersensitivity to study agents.
• Systemic immunocompromised state (uncontrolled diabetes, Human immune defecinicy virus).
• Poor compliance expected with follow-up.