NCT Number: NCT06928168
The approach of a competition can be associated to a decrease in sleep duration and quality which can negatively impact athlete's performance and health (injury risk, fall, accident). Ultra-endurance competitions even involve partial and/or total sleep deprivation over one or several nights. Studied investigating this question suggest that endurance performance under sleep deprivation is altered, mainly because of an effect on the rate of perceived exertion (RPE), which regulates effort intensity. One of the methods used by athletes to limit the impact of sleep deprivation in competition is to implement sleep extension in the days prior to a competition. However, few studies have investigated the impact of sleep deprivation et its reproducibility on performance and fatigue during a prolonged running exercise, as well as the efficiency of prior sleep extension. The importance of such a preventive measure might also depend on individual resistance to sleep deprivation, which is variable between persons and could have genetic determinants. This aspect remains under-studied, particularly regarding the impact of sleep deprivation on physical performance. Therefore, this study aims at investigating the effects of sleep deprivation and prior sleep extension on prolonged duration performance.
Interested in participating?
Request Info18 year–50 year
All sexes
Interventional
Not applicable
Saint-Etienne, 42055, France
Location status: Recruiting
Clément FOSCHia, MD
SUB_INVESTIGATOR
Diana RIMAUD, science Doctor
CONTACT
0477120467 ext. 33
Léonard FEASSON, PhD
CONTACT
04 77 12 03 83 ext. 33
Léonard FEASSON, PhD
PRINCIPAL_INVESTIGATOR
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
This group will perform an incremental running test, conducted until exhaustion, in: - a control condition (usual sleep) - a one-night condition of partial sleep deprivation - a one-night partial sleep deprivation condition with 5 nights of prior extension. The order of conditions will be randomized.
This group will perform an incremental running test, conducted until exhaustion, in: - a control condition (usual sleep) - a one-night condition of partial sleep deprivation - a one-night partial sleep deprivation condition with 5 nights of prior extension. The order of conditions will be randomized.
This group will perform an incremental running test, driven to exhaustion, after a night of total sleep deprivation twice, at least two weeks apart.
Time frame: Day 7
Sporting performance, measured by the duration of exercise in a time-limited incremental effort test in running to exhaustion, i.e. the inability to maintain the imposed pace.
Time frame: Day 7
Repeatability of sleep deprivation effects will be assessed within the REP group by comparing performance on the time limit test (in minutes) after each sleep deprivation.
Time frame: DAy 1
The influence of genetic polymorphism will be evaluated via the effects of sleep deprivation according to the genetic polymorphism of the ADORA2A, TNFα and COMT genes
Time frame: DAy 7
Neuromuscular fatigue will be assessed by the loss of isometric knee extensor muscle strength measured before and just after the time limit test. To characterize the origin of neuromuscular fatigue, electrically evoked forces from peripheral nerve stimulation and electrical muscle activity (EMG) will be measured to quantify central and peripheral fatigue.
Time frame: DAy 7
Sleepiness will be assessed using the Epworth Sleepiness Scale, and perceived exertion will be rated on a Borg scale from 6 to 20 during submaximal exercise prior to the time limit test, and regularly during the test.
Time frame: DAy 7
Perceived fatigue will be rated on a 0-10 scale before and after the time limit test.
Time frame: Day 7
Motor function will be assessed during 40 minutes of submaximal exercise at an intensity corresponding to the first ventilatory threshold (SV1) preceding the time limit test. Running biomechanics will be investigated by measuring ground reaction forces (in Newtons) using force platforms integrated into an instrumented treadmill.
Time frame: Day 7
Motor function will be assessed during 40 minutes of submaximal exercise at an intensity corresponding to the first ventilatory threshold (SV1) preceding the time limit test. The energy cost of running (Cr, in J/kg/m) will be quantified by measuring gas exchanges over a 5-minute period.
Time frame: Day 7
Cognitive function will be assessed before, during and after exercise using Psychomotor Vigilance Task (PVT)
Time frame: Day 7
Cognitive function will be assessed before, during and after exercise using concentration test (sustained attention task).
Time frame: Day 7
Cognitive function will be assessed before, during and after exercise using a battery of tests including inhibition test (Go-no Go task)
Contact information is provided by the study sponsor or research team.
Diana RIMAUD, science Doctor
CONTACT
0477120467 ext. 33
Léonard FEASSON, PhD
CONTACT
04 77 12 03 83 ext. 33
Centre Hospitalier Universitaire de Saint Etienne
Other
Effect of Sleep Extension in Prevention to Sleep Deprivation on Running Endurance Performance
Acronym: SLEEPERF
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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